Carcinoma in situ in a lateral cervical cyst

Zimmermann, Corinna; Domarus, Helmut von; Moubayed, Pierre

doi:10.1002/hed.10118

Cited by 30 publications

(15 citation statements)

References 36 publications

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“…Zimmerman documented the in situ carcinoma stage without clear invasion, which confirms the abovementioned etiopathogenetic theory [3]. The histological assessment was the strongest argument support ing the branchiogenic etiology in our case as well.…”

Section: Discussionsupporting

confidence: 88%

Primary Branchiogenic Carcinoma

Hořáková¹,

Velecký²,

Pažourková³

et al. 2018

Klin Onkol

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SummaryBackground: Primary branchiogenic carcinoma (BC) is an exceptional dia gnostic entity. In most cases, suspicion of BC is confirmed to be a cystic lymph node metastasis of an occult primary tumor. Martin and Khafif therefore established dia gnostic criteria, emphasiz ing above all the importance of a histologically assessed transformation of cystic lin ing epithelium into an invasive squamous cell carcinoma in one pathological lesion after the exclusion of a primary tumor. Case report: We present a case report of an 80-year-old patient who presented for a follow-up for an 8-year history of a benign lateral cervical cyst, which was not surgically treated due to the patient's high risk of complications from general anesthesia. In spite of the risk, the surgery was performed after a sudden clinical progression, and surprisingly, post-operative histology revealed BC. Conslusion: BC is a very rare entity, strictly defined by Martin's and Khafif's criteria. Recently, BCs have been presented in the literature only as unique case reports respond ing as in our patient to the above mentioned criteria, with particular emphasis on the histological aspect, imag ing the cystic lin ing epithelium transform ing into an invasive squamous cell carcinoma in one pathological lesion and a long history without evidence of primary tumor.

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Section: Discussionsupporting

confidence: 88%

Primary Branchiogenic Carcinoma

Hořáková¹,

Velecký²,

Pažourková³

et al. 2018

Klin Onkol

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“…The most important clinical differential diagnosis for our case included BCC and metastatic cystic squamous cell carcinoma;, although not always the case, the latter is more frequently observed in an older age group compared with the present patient [1][2][3][4].…”

Section: Discussionmentioning

confidence: 59%

“…Histologically, BCC are lined by squamous or respiratory epithelium, frequently associated with subepithelial lymphocytes [4]. Fibroinflammatory reaction surrounding BCC is a frequent finding, especially if the cyst is ruptured or infected [2].…”

Section: Discussionmentioning

confidence: 99%

“…However their existence is controversial since these might be mimicked by metastatic cystic carcinomas, which are frequent lesions of the lateral neck in adults [1][2][3][4]. A malignant tumor, especially metastatic cystic squamous cell carcinoma, should always be considered in the differential diagnosis of a cystic lateral neck mass, particularly in patients older than 40 [1,2].…”

Section: Introductionmentioning

confidence: 99%

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Branchial Cleft Cyst with Xanthogranulomatous Inflammation

Sarıoğlu

Ünlü

Adalı

et al. 2011

Head and Neck Pathol

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Xanthogranulomatous inflammation (XGI) is a special type of inflammation presenting as mass lesions and mimicking malignant tumors. It is rarely described in the head and neck region, and to the best of our knowledge, there are no cases associated with branchial cleft cyst. A 39-year-old woman with an infiltrative cystic neck mass that radiologically mimicks a malignant tumor is herein presented. The histopathologic diagnosis was a branchial cleft cyst with XGI. XGI may be associated wih branchial cleft cysts. Patients may present with radiologic findings mimicking an invasive malignant tumor, and should be taken into account during the differential diagnosis with cystic squamous cell carcinoma.

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“…1 Los quistes ltero-cervicales malignos son muy raros y suelen tener su origen en tumores metastáticos provenientes principalmente de carcinomas de la región oro-naso-faríngea, del tiroides y glándulas salivares 2, 3 o en el raro y controvertido carcinoma branquiogénico primario. [4][5][6] Como en este caso se confirmó posteriormente, existe la posibilidad de hallarnos ante la infrecuente presentación primaria de un carcinoma papilar oculto tiroideo como metástasis cervical quística.…”

Section: Discussionunclassified