Carcinoma in situ of the cervix

Mussey, Elizabeth; Soule, Edward H.

doi:10.1016/0002-9378(59)90041-9

Cited by 42 publications

(7 citation statements)

References 13 publications

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“…The three patients with proven histological extension to the vault have had negative cytology following excision of the vault and it is not intended to use radiation as advised by some authors (Margulis et al, 1962;Mussey and Soule, 1959). Cytology has thus demonstrated that the chances of recurrence of carcinoma in situ after hysterectomy are real and that cases so managed need just as careful follow-up as those treated conservatively.…”

Section: 3 and 6 Yearsmentioning

confidence: 99%

CERVICAL CYTOLOGY AND CARCINOMA IN SITU

Green

1965

BJOG

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IF cytology is helping to overcome one problem in cervical cancer-that of early diagnosis-it is creating many others. It will be the aim of this paper, based on observations made on a series of 278 cases of cervical carcinoma in situ dealt with at the National Women's Hospital in the 12 years 1951-62 and all having a minimum follow-up period of 18 months, to discuss some of the problems cytology has created in the discovery of 237 of them. Tables I and I1 show what cytology has accomplished in this hospital in 8 years; the number of smears examined annually has risen from 3,250 in 1955 to 27,820 in 1962. It is interesting to note that as increasing numbers of the population are screened the detection rate for preclinical cancer is falling. Possibly the fall is contributed to by increasing conservatism in the histological diagnosis of carcinoma in silu as increasing numbers of cases are revealed by An additional 36 cases of intra-epithelial cancer were treated which were revealed by cytology smears examined in other laboratories, so that of the 278 cases dealt with 237 (85-3 per cent) owe their diagnosis to cytology. In the years 1960-62 the proportion of cases discovered by cytology was 95.8 per cent. cytology. RESULTS FROM 8 YEARS OF CYTOLOGY

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Section: 3 and 6 Yearsmentioning

confidence: 99%

CERVICAL CYTOLOGY AND CARCINOMA IN SITU

Green

1965

BJOG

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“…Such reports in several cases in this series were the first and only indication of the presence of pre-invasive carcinoma and must therefore be taken seriously. Several recent papers testify to the clinical difficulties associated with these suspicious or atypical smears (Estrada et al, 1959;Mussey and Soule, 1959;Hall and Rosen, 1960;Marsan et al, 1960). Their incidence is placed as high as 5 to 8 per cent of all smears.…”

Section: Aid To Cytologymentioning

confidence: 99%

COLPOSCOPY, CERVICAL CARCINOMA IN SITU AND THE GYNAECOLOGIST

Coppleson

1964

BJOG

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“…Invasive carcinoma occurs in patients with an average age of approximately 50 years and carcinoma in situ is thought to be present for ten to twelve years before the onset of invasion (38.7 years, Hertig and Younge, 1952;38 years, Scaramucci et al, 1958;38 years, McKay et al, 1959). Even with a possibly later onset in life (43.4 years, Mussey and Soule, 1959;42 years, Henderson and Buck, 1961) there still remain at least 5 years during which the progression or regression of carcinoma in situ can be assessed. It has been shown by Kern (1959) that it is possible to differentiate, by cytological methods, between carcinoma in situ and invasive carcinoma.…”

Section: Clinical Examinationmentioning

confidence: 99%

CARCINOMA IN SITU—DIAGNOSIS AND PROGNOSIS

Kirkland

1963

BJOG

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Carcinoma in situ of the cervix

Cited by 42 publications

References 13 publications

CERVICAL CYTOLOGY AND CARCINOMA IN SITU

CERVICAL CYTOLOGY AND CARCINOMA IN SITU

COLPOSCOPY, CERVICAL CARCINOMA IN SITU AND THE GYNAECOLOGIST

CARCINOMA IN SITU—DIAGNOSIS AND PROGNOSIS

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