“…Park, in 1952, andAsherson, in 1953, reported on patients with apparent "cardiospasm", in whom gastric cancer was eventually diagnosed. [5,6] Incidence and prevalence Owing to the lack of a large series, there are no reliable epidemiological data on the incidence and prevalence of the disease. Campo et al in their review reported 4.7% of patients who fulfill the manometric criteria of achalasia were eventually diagnosed with a malignant disease, directly or indirectly involving the cardia, or following antireflux surgery.…”