Carcinoma of the Breast

Moore, Francis D.; Woodrow, Steven I.; Aliapoulios, Menelaos A.; Wilson, Richard E.

doi:10.1056/nejm196708312770904

N Engl J Med

1967

DOI: 10.1056/nejm196708312770904

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Carcinoma of the Breast

Francis D. Moore¹,

Steven I. Woodrow²,

Menelaos A. Aliapoulios³

et al.

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1970

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Cited by 15 publications

References 28 publications

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The use of cautery in “bloodless” radical mastectomy

Kakos

James

1970

Cancer

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Several different forms of operative procedures for carcinoma of the breast have been advocated, but radical mastectomy remains the one most often recommended. Blood loss during this procedure is frequently high, often necessitating transfusion. Unfortunately, complications of the latter have been significant and justifiably have continued to receive attention in literature. In this study, blood loss and wound healing, with and without the use of electrocautery, in radical mastectomy were evaluated from both clinical and laboratory studies. Fifty patients who underwent radical mastectomy were studied for blood loss, transfusions received, and wound healing. Technique was identical except that one half of the patients had thin skin flap elevation via electrocautery rather than by sharp dissection. The average blood replacement was 160 ml per patient when cautery was used vs. 960 ml per patient when cautery was not used. The postoperative hemoglobin and hematocrit values were statistically similar for both groups. Wound healing was not affected. In addition, a laboratory study, utilizing skin incisions in dogs using scalpel and cautery, was performed. No appreciable difference in healing was noted either on gross or microscopic inspection. The use of electrocautery, therefore, for skin flap elevation during radical mastectomy is recommended.

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The use of cautery in “bloodless” radical mastectomy

Kakos

James

1970

Cancer

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Single and combination nonhormonal chemotherapy in breast cancer

Carter

1972

Cancer

138

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The quality of survival in breast cancer: A case-control comparison

Craig

Comstock

Geiser

1974

Cancer

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Quality of survival as defined by physical and psychosocial criteria was found to be remarkably similar among 134 breast cancer patients and 260 controls. Most of the cases had been diagnosed 5 or more years prior to this study. Physical disability was reported by 19% of the cases and 16% of the controls. The slight excess of disability among the cases was related to surgical treatment. There was no evidence of increased psycho‐social disability among the cases. The principal effect of breast cancer was to triple mortality over a 28‐month period. In both cases and controls, subsequent mortality was associated with reports of disability and ill health on the questionnaire but not with psycho‐social variables, with the possible exception of a pessimistic view of the future.

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Carcinoma of the Breast

Cited by 15 publications

References 28 publications

The use of cautery in “bloodless” radical mastectomy

The use of cautery in “bloodless” radical mastectomy

Single and combination nonhormonal chemotherapy in breast cancer

The quality of survival in breast cancer: A case-control comparison

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