Carcinoma of the lung in HIV-positive patients: findings on chest radiographs and CT scans.

White, Charles S.; Haramati, Linda B.; Elder, K. H.; Karp, Jacqueline; Belani, Chandra P.

doi:10.2214/ajr.164.3.7863877

Cited by 38 publications

(15 citation statements)

References 3 publications

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“…There is also a striking male preponderance. The documented cell types are similar to those found in young sero-negative patients and are most commonly adenocarcinomas [76,77,78,82]. Unlike KS and lymphoma, no associated mutagenic viral agent has been identified in relation to the development of lung cancer in AIDS patients.…”

Section: Lung Carcinomamentioning

confidence: 77%

“…There are several reported series of lung carcinoma occurring in patients with AIDS [73,76,77,78,79,80]. It is not clear from these studies whether AIDS patients have an increased risk of developing primary malignant lung tumours.…”

Section: Lung Carcinomamentioning

confidence: 99%

“…The HIV infected patients are typically younger at the time of diagnosis [78,79], have more advanced disease [77] and a shorter survival time than non-HIV-infected patients who present with lung cancer [77,82]. There is also a striking male preponderance.…”

Section: Lung Carcinomamentioning

confidence: 99%

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Computed tomography of the thorax in HIV disease

Padley

King

1999

European Radiology

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A wide variety of thoracic disorders can arise in patients infected with the human immunodeficiency virus (HIV), although recent developments in the therapeutic management of AIDS patients has resulted in a changing pattern of chest disease. The use of CT in the diagnosis and management of these thoracic manifestations is discussed along with the CT appearances of the various infectious and non-infectious complications of the acquired immune deficiency syndrome (AIDS) which are commonly encountered in clinical practice.

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Section: Lung Carcinomamentioning

confidence: 77%

Section: Lung Carcinomamentioning

confidence: 99%

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Computed tomography of the thorax in HIV disease

Padley

King

1999

European Radiology

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“…The median age of lung cancer patients living with HIV is reportedly 45-50 years, whereas for those without HIV it is 62 years, although recent surveillance has reported a median age of 60 years (22,23). In the post-antiretroviral era, lung cancer patients living with HIV are younger and recent surveillance has demonstrated that the age of these patients is similar to that of the non-HIV population (7).…”

Section: Discussionmentioning

confidence: 99%

Single-institutional experience of clinicopathological analysis and treatment for lung cancer patients with human immunodeficiency virus infection

Takahashi

Okuma

Watanabe

et al. 2017

Molecular and Clinical Oncology

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“…[64][65][66][67] Among 15 such patients, parenchymal masses and nodules were the commonest features (67%) on chest radiographs and computerized tomography (CT). 65 Masses were peripheral in 11 cases (73%) and were located in the upper lobes in 10 cases (67%).…”

Section: Clinical Characteristicsmentioning

confidence: 99%

Lung Cancer in HIV Infection

Mani

Aboulafia

2014

Cancers in People With HIV and AIDS

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Lung cancer is the most prevalent non-AIDS-defining malignancy in the HAART era. Smoking plays a significant role in the development of HIV-associated lung cancer, but the cancer risk is 2-4 times greater in HIV-infected persons than in the general population, even after adjusting for smoking intensity and duration. Lung cancer is typically diagnosed a decade or more earlier among HIV-infected persons (mean age, 46 years) compared to those without HIV infection. Adenocarcinoma is the commonest histological subtype, and the majority of patients are diagnosed with locally advanced or metastatic carcinoma. Since pulmonary infections are common among HIV-infected individuals, clinicians may not suspect lung cancer in this younger patient population. Surgery with curative intent remains the treatment of choice for early stage disease. Although there is increasing experience in using radiation and chemotherapy for HIV-infected patients who do not have surgical options, there is a need for prospective studies for this population frequently excluded from participating in cancer trials. Evidence-based treatments for smoking-cessation with demonstrated efficacy in the general population must be routinely incorporated into the care of HIV-positive smokers.

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Carcinoma of the lung in HIV-positive patients: findings on chest radiographs and CT scans.

Cited by 38 publications

References 3 publications

Computed tomography of the thorax in HIV disease

Computed tomography of the thorax in HIV disease

Single-institutional experience of clinicopathological analysis and treatment for lung cancer patients with human immunodeficiency virus infection

Lung Cancer in HIV Infection

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