Carcinoma of the penis

Bassett, John W.

doi:10.1002/1097-0142(195205)5:3<530::aid-cncr2820050315>3.0.co;2-9

Cited by 30 publications

(6 citation statements)

References 27 publications

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Section: The Role Of Lymphadenectomymentioning

confidence: 99%

“…With this strict scheme the author's group have been able to salvage almost all patients who develop lymph node metastasis after treatment of the primary tumour [14]. Nodal recurrences after 3 years are extremely rare [41,42]. Even if lymphadenectomy is restricted to patients at high risk of developing metastasis, lymphadenectomy is bene®cial to only 40%; in 60% the surgery is unnecessary, as no metastasis is found in the lymphadenectomy specimen [33].…”

Section: The Role Of Lymphadenectomymentioning

confidence: 99%

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Lymphadenectomy for squamous cell carcinoma of the penis. Part 2: The role and technique of lymph node dissection

Horenblas

2001

BJU International

175

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Section: The Role Of Lymphadenectomymentioning

confidence: 99%

Section: The Role Of Lymphadenectomymentioning

confidence: 99%

Lymphadenectomy for squamous cell carcinoma of the penis. Part 2: The role and technique of lymph node dissection

Horenblas

2001

BJU International

175

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“…We evaluated some prognostic factors for global survival (GS) and cancer-specific survival (CSS) in a historical series of patients not submitted to lymphadenectomy and that did not show lymph node metastasis in a minimum follow-up of three years. The occurrence of lymph node metastasis following that period is extremely rare (6–8). …”

Section: Introductionmentioning

confidence: 99%

Tumor histologic grade is the most important prognostic factor in patients with penile cancer and clinically negative lymph nodes not submitted to regional lymphadenectomy

et al. 2016

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Introduction:The presence and extension of inguinal lymph node metastasis are the main prognostic factors in patients with penile cancer. Physical exam and image exams are not adequate to evaluate inguinal lymph nodes and many patients are submitted to non-therapeutic lymphadenectomies. However, it is known that not all patients with clinically or histologically negative inguinal lymph nodes evolve favorably.Casuistic and Methods:the authors evaluated the clinical and pathologic characteristics of 163 patients with penile carcinoma and clinically negative inguinal lymph nodes followed for three or more years and their impact on global survival (GS) and cancer-specific survival (CSS) in the 10-year follow-up. Primary pathologic tumor stage (p=0.025) and the presence of high grade of tumor differentiation (p=0.018) were predictive of CSS. The presence of high grade tumor was an independent specific prognostic factor of death risk (RR 14.08; p=0.019).Conclusion:high histologic grade was an independent predictive factor of specific death risk in patients with penile carcinoma and clinically negative lymph nodes followed for three or more years.

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“…Some studies have suggested penile carcinoma is four times more common in whites compared with African Americans. 2,3 In contrast, Beggs and Spratt 4 reported no difference in race presentation percentage in 1964. However, in 1979, Muir and Nectoux 5 found a 2:1 African-American predominance.…”

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confidence: 98%

Squamous cell carcinoma of the penis

Rippentrop

Joslyn

Konety

2004

Cancer

124

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BACKGROUND Penile carcinoma is uncommon. Therefore, obtaining meaningful epidemiologic data requires analysis of large, multisource databases. The authors examined the association between different demographic variables and the prevalence, presentation, and survival of patients with penile squamous cell carcinoma in the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database. METHODS The SEER database represents 12% of the U.S. population. The database included 1605 patients with a diagnosis of penile squamous cell carcinoma between 1973 and 1998. The variables analyzed were age, race, marital status, stage at presentation, type of surgery, performance of lymphadenectomy, and disease‐specific survival. RESULTS Of 1605 patients, 37% presented with carcinoma in situ (CIS), 39% with localized disease, 13% with regional disease, 2.3% with distant disease, and 7.9% of the patients were unstaged. The percentage of patients presenting with CIS and localized disease increased and decreased yearly, respectively. African Americans represented 9.9% of the population and tended to present at a younger age and with a higher stage of disease, and their cancer‐specific survival was shorter in all stages. However, these associations were statistically significant only for men with regional disease. Marital status was documented for 1394 patients (87%). The majority (84%) had a history of marriage and presented at an earlier stage of disease and had higher disease‐specific survival in the localized (P = 0.0002) and regional stages (P = 0.0010) of disease. CONCLUSIONS The diagnosis of penile carcinoma significantly reduced survival. African‐American men presented with a higher stage of disease and statistically significant decreased survival, whereas previously or currently married men presented at an earlier stage of disease and sought more aggressive treatment. Cancer 2004. © 2004 American Cancer Society.

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Carcinoma of the penis

Cited by 30 publications

References 27 publications

Lymphadenectomy for squamous cell carcinoma of the penis. Part 2: The role and technique of lymph node dissection

Lymphadenectomy for squamous cell carcinoma of the penis. Part 2: The role and technique of lymph node dissection

Tumor histologic grade is the most important prognostic factor in patients with penile cancer and clinically negative lymph nodes not submitted to regional lymphadenectomy

Squamous cell carcinoma of the penis

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