2013
DOI: 10.1111/anae.12099
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Cardiac arrest in an obstetric patient using remifentanil patient‐controlled analgesia

Abstract: Summary This case report describes the management of a patient, diagnosed with an intrauterine death at 31 weeks’ gestation, who suffered a cardiorespiratory arrest during her induced labour while using a remifentanil PCA. She made a full recovery from resuscitation which included a peri‐mortem caesarean section.

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Cited by 51 publications
(18 citation statements)
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“…Furthermore, in addition to the safety features mentioned in previous correspondence [1,3], we suggest that an initial 20-lg bolus of remifentanil may be safer in opioidna€ ıve patients. While it is open to debate whether remifentanil PCA should be considered equivalent to central neuraxial analgesia, it was initially introduced to allow dynamic analgesia for women in labour with contraindications to epidural analgesia, without adversely affecting their babies [4].…”
supporting
confidence: 53%
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“…Furthermore, in addition to the safety features mentioned in previous correspondence [1,3], we suggest that an initial 20-lg bolus of remifentanil may be safer in opioidna€ ıve patients. While it is open to debate whether remifentanil PCA should be considered equivalent to central neuraxial analgesia, it was initially introduced to allow dynamic analgesia for women in labour with contraindications to epidural analgesia, without adversely affecting their babies [4].…”
supporting
confidence: 53%
“…Although the case report recently published by Marr and co-authors [1] emphasises important safety aspects when using remifentanil for labour analgesia, we feel the title and summary of the report are misleading as they imply that remifentanil was the problem. A more appropriate (though admittedly less snappy) description might be 'Cardiac arrest in an obstetric patient with diagnosed intrauterine death using concomitant paracetamol, codeine, Entonox, diamorphine plus remifentanil PCA', which emphasises the risk of administering concomitant potent opioids and/or non-opioid analgesics when remifentanil is used.…”
mentioning
confidence: 88%
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“…Bonner et al 53 Respiratory arrest in patient using remifentanil in PCA Marr et al 54 Cardiorespiratory arrest during induced labour while using a remifentanil PCA in patient diagnosed with an intrauterine death at 31 weeks' gestation PCA -Patient controlled analgesia Table 6. Meta-analysis of study results comparing VAS between t=0 and t=1 hour for remifentanil.…”
Section: Referencementioning
confidence: 99%
“…Sus características farmacocinéticas lo convierten en alternativa para administrar en PCA en pacientes con contraindicación para la analgesia neuroaxial 65,[74][75][76][77] , aunque se necesitan más estudios para valorar su eficacia y seguridad 78 . El principal efecto adverso es la depresión respiratoria maternal (por tanto se necesita monitorización continua y disponibilidad de oxígeno por si fuese necesario) 79 , habiéndose descrito una parada cardiorrespiratoria 80 . También pueden aparecer náuseas (incidencia variable), prurito moderado (que no suele necesitar tratamiento) 79 y sedación 81 .…”
Section: Opioidesunclassified