Cardiac-Gated Phase MR Imaging of Aqueductal CSF Flow

Mascalchi, Mario; Ciraolo, L.; Tanfani, G.; Taverni, N; Inzitari, Domenico; Gf, Siracusa; Pozzo, Dal

doi:10.1097/00004728-198811000-00003

Cited by 31 publications

(20 citation statements)

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“…Among other possibilities, this may be seen in normal pressure hydrocephalus, which clinically can be almost indistin guishable from A D when presenting with dementia alone. A study on the C SF dynamics in the same groups of patients utilizing cardiac-gated phase MRI of aqueductal C SF flow [28] is proposed. This presumably will convey more information about the pathophysiology of PVH in clinically diagnosed A D .…”

Section: Discussionmentioning

confidence: 99%

Comparison of Magnetic Resonance Imaging in Alzheimer’s Disease, Vascular Dementia and Normal Aging

Schmidt

1992

Eur Neurol

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MRI scans of 27 patients with probable Alzheimer’s disease (mean age 68.2 years), 31 patients with vascular dementia (mean age 69.9 years) and 18 normal controls (mean age 66.3 years) were compared to evaluate possible distinguishing parenchymal abnormalities among these groups. Atrophy was quan-titated by subjective rating, linear and volumetric measurements. A number of findings were significantly more common in vascular dementia than in the other subsets. These included (1) basal ganglionic/thalamic hyperintense foci, (2) thromboembolic infarctions, (3) confluent white matter and (4) irregular periventricular hyperintensities. Signal abnormalities on intermediate T₂-weighted scans in the uncal-hippocampal or insular cortex were frequently and almost exclusively noted in Alzheimer’s disease. Moderate and severe cortical and ventricular atrophy and a third ventricular to intracranial width ratio larger than 7 % were good discriminators between demented groups and normally aging controls. Selective atrophy measurements, however, failed to separate dementia syndromes. These results suggest that MRI has the potential to increase the accuracy of the clinical diagnosis of Alzheimer’s disease and vascular dementia.

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Section: Discussionmentioning

confidence: 99%

Comparison of Magnetic Resonance Imaging in Alzheimer’s Disease, Vascular Dementia and Normal Aging

Schmidt

1992

Eur Neurol

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“…Since the aqueduct of Sylvius can be considered a CSF vessel, about 15 mm in length and 1-2 mm in width, that connects the third and the fourth brain ventricles (Brinkmann et al, 2000;Flyger and Hjelmquist, 1957;Longatti et al, 2007;Mascalchi et al, 1988), this technique has also been applied to aqueductal CSF flow Brinkmann et al, 2000;Mark and Feinberg, 1986;Mascalchi et al, 1988). The aqueduct is a suitable location for the characterization of CSF flow since it is a narrow structure, which results in a higher velocity (several cm/s) than, for example, in the third ventricle.…”

Section: Magnetic Resonance Imaging Methodsmentioning

confidence: 99%

“…This assumption has rarely been reported in literature (Di Chiro, 1964;Weed, 1914). It is believed that CSF flow is augmented by the ciliary action of the ventricular ependyma, vascular, choroidal and respiratory pulsations, cardiac systole and diastole and the hydrostatic pressure gradient that exists between the CSF and the venous system (Bering, 1962;Bering and Satto, 1963;Bhadelia et al, 1995;Di Chiro, 1964;Du Boulay, 1966;Du Boulay et al, 1972;Florez et al, 2006;Lee et al, 2004;Mascalchi et al, 1988;Milhorat, 1975;O'Connel, 1970;Ohara et al, 1988;Scollato et al, 2008;Thomsen et al, 1990).…”

Section: Formation Rate Of Cerebrospinal Fluid As the Main Generator mentioning

confidence: 99%

The formation of cerebrospinal fluid: Nearly a hundred years of interpretations and misinterpretations

Orešković

Klarica

2010

Brain Research Reviews

299

274

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“…4,42,43 Initially, CSF flow was only qualitatively described as the flow-void sign that is best appreciated in areas of narrowing within the ventricular system such as the aqueduct.…”

Section: Discussionmentioning

confidence: 99%

“…3,17,28,60 The results of these measurements have yielded considerable information on the physiology of the normal CSF circulation. 1,6,7,9,17,23,42,43 In addition, pathological CSF flow dynamics in communicating and obstructive hydrocephalus, 11,22,[32][33][34]44,54 Chiari malformation, 8 cystic lesion, 15 and cervical spondylosis 60 have been analyzed. With the increasing frequency of neuroendoscopic procedures, cine MR imaging has been recommended for evaluating the patency of third ventriculostomies.…”

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confidence: 99%

Analysis of aqueductal cerebrospinal fluid flow after endoscopic aqueductoplasty by using cine phase-contrast magnetic resonance imaging

Schroeder¹,

Schweim²,

Schweim³

et al. 2000

FOC

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Object The purpose of this prospective study was to evaluate aqueductal cerebrospinal fluid (CSF) flow after endoscopic aqueductoplasty. In all patients, preoperative magnetic resonance (MR) imaging revealed hydrocephalus caused by aqueductal stenosis and lack of aqueductal CSF flow. Methods In 14 healthy volunteers and in eight patients with aqueductal stenosis who had undergone endoscopic aqueductoplasty, aqueductal CSF flow was investigated using cine cardiac-gated phase-contrast MR imaging. For qualitative evaluation of CSF flow, the authors used an in-plane phase-contrast sequence in the midsagittal plane. The MR images were displayed in a closed-loop cine format. Quantitative through-plane measurements were performed in the axial plane perpendicular to the aqueduct. Evaluation revealed no significant difference in aqueductal CSF flow between healthy volunteers and patients with regard to temporal parameters, CSF peak and mean velocities, mean flow, and stroke volume. All restored aqueducts have remained patent 7 to 31 months after surgery. Conclusions Aqueductal CSF flow after endoscopic aqueductoplasty is similar to aqueductal CSF flow in healthy volunteers. The data indicate that endoscopic aqueductoplasty seems to restore physiological aqueductal CSF flow.

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Cardiac-Gated Phase MR Imaging of Aqueductal CSF Flow

Cited by 31 publications

References 0 publications

Comparison of Magnetic Resonance Imaging in Alzheimer’s Disease, Vascular Dementia and Normal Aging

Comparison of Magnetic Resonance Imaging in Alzheimer’s Disease, Vascular Dementia and Normal Aging

The formation of cerebrospinal fluid: Nearly a hundred years of interpretations and misinterpretations

Analysis of aqueductal cerebrospinal fluid flow after endoscopic aqueductoplasty by using cine phase-contrast magnetic resonance imaging

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