Cardiac Implantable Electronic Device–Related Infection Due to Granulicatella adiacens

Abstract

Cardiac implantable electronic device–related infection is clinically challenging. Curative treatment commonly includes system removal. A case caused by Granulicatella adiacens occurred in a 32-year-old woman. Clinical course, literature review, and biofilm investigations enabled successful antibiotic management without system removal.

Granulicatella adiacens as an Unusual Cause of Empyema: A Case Report and Review of Literature

“…Using the inclusion and exclusion criteria, 24 literature were found relevant and included in the review. 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Clinical details of all published literature are compiled in the Table 1 . As per the review of literature of last 10 years, G. adiacens is found to be the cause of various infections such as bacteremia, endocarditis, osteomyelitis, septic arthritis, discitis, prosthetic joint infections, carbuncle, bacterascites (spontaneous bacterial peritonitis), dacryocystitis, and abscess.…”

Precision Medicine in the Diagnosis and Management of Orthopedic Biofilm Infections

“…Unfortunately, there is no such simple linearity because many technical, material, and environmental factors influence the microbiological result, as outlined earlier. Nonetheless, a similar concept was recently applied on a case basis in a context other than orthopedic infections, namely, in a patient with a cardiac device-related infection and conduit valve prosthesis endocarditis caused by nutritionally variant streptococci (87). Biofilm production was investigated on three different materials (bone cement, glass, plastic), and several different culture media.…”