Cardiac output determination in children: equivalence of the transpulmonary thermodilution method to the direct Fick principle

Abstract

We demonstrated the equivalence of CI measurement by transpulmonary thermodilution and the Fick principle in children. This new method may improve hemodynamic monitoring and management in seriously ill children.

Cardiac Output Measurement Using a Modified Carbon Dioxide Fick Method: A Validation Study in Ventilated Lambs

“…These methods differ in applicability due to technical and size constraints and reliability (1)(2)(3). In comparison with published data concerning bias and precision of several methods of cardiac output measurement in animals (19 -22), children (23)(24)(25)(26)(27)(28)(29)(30), and adults (31)(32)(33)(34)(35)(36)(37)(38), this study produced favorable results.…”

Prognostic value of extravascular lung water index in critically ill children with acute respiratory failure

“…EVLWi measurements thus obtained are comparable with the thermo-dye dilution technique and with the gravimetric method, the latter being considered the gold standard for EVLWi assessment [15].The thermodilution method for hemodynamic monitoring is particularly appealing for use in pediatrics, as it avoids pulmonary artery catheterization, which carries a significant risk [16]. It must be said that thermodilution also has its drawbacks.…”

Extravascular lung water measurements and hemodynamic monitoring in the critically ill: bedside alternatives to the pulmonary artery catheter

“…In children, measurements of CO tp have been compared with calculations based on the Fick principle, often considered the gold standard for estimating CO (79,103). For instance, in a study by Pauli et al (79), the two methods were highly correlated (R 2 ϭ 0.99), with a bias of only 0.036 l⅐min Ϫ1 ⅐m…”