Cardiac Papillary Fibroelastoma as a Cause of Embolic Stroke: Ultrasound and Histopathological Characteristics

Abstract

Abstract

Cardiac Papillary Fibroelastoma: Source of Cerebral Embolism Treated With Intravenous Thrombolysis

“…Despite this, anticoagulant therapy is recommended for stroke patients with PFE up to the day of the surgical resection. 5 Clinical symptoms and physical examination in presented patient did not suggest a diagnosis of tumor emboli. There are 2 reports about intra-arterial thrombolysis in patients with atrial myxoma and PFE, which were successfully recanalized, 3,6 and only one case of myxoma in which an intravenous thrombolytic agents have been used with complete recovery of neurological deficit and without complications.…”

Papillary fibroelastoma situated in the subvalvular structure of the mitral valve

“…The aorta was cross-clamped, and combined antegrade and retrograde blood cardioplegia was used to preserve the cardiac tumors. [2][3] Cardiac papillary fibroelastomas are rare benign cardiac tumors that have an incidence of 0.001-0.030% and are accepted as the most common primary valvular solitary tumor. [3,5,6] They originate from endocardial tissue [5] and are most frequent located in the aortic valve (29%), followed by the mitral valve (25%).…”

“…[2][3] Cardiac papillary fibroelastomas are rare benign cardiac tumors that have an incidence of 0.001-0.030% and are accepted as the most common primary valvular solitary tumor. [3,5,6] They originate from endocardial tissue [5] and are most frequent located in the aortic valve (29%), followed by the mitral valve (25%). [2,5,6] However, chordal and subvalvular involvement of the mitral valve rarely occurs with CPF.…”

“…[1] They are the third most common primary cardiac tumor, following myxomas and lipomas, and the most common primary valvular tumor. [2][3][4][5] They usually occur on the left side of the heart, especially on the aortic valve. [6] However, involvement of the subvalvular structure of the mitral valve is uncommon.…”

“…Although CPFs are benign in nature, they can cause severe thromboembolic complications regardless of the tumor size. [1,3,5,7,8] Therefore, surgical treatment is recommended to prevent this from happening. [2,4] Here we report a patient with papillary fibroelastoma of the subvalvular structure of the mitral valve that was treated surgically.…”