Cardio Protective Effect of &lt;i&gt;Solanum nigrum&lt;/i&gt; Linn. in Isoproterenol Induced  Myocardial Infarction in Rat

Shaik, Sameer Amjad; Huded, Shivaprasad; Fathima, Asra; Preran, K.H.; Fathima, Syeda Juveriya; Khanum, Farhath

doi:10.4314/star.v4i4.11

Cited by 7 publications

(1 citation statement)

References 2 publications

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“…The in vivo study results have decreased QT interval (duration of ventricular electrical systole) and heart rate due to a decrease in myocardial damage. A reduction in biochemical parameters like triglyceride and cholesterol was also observed by the hydroalcoholic extract of the plant and thus confirms cardioprotective action [ 169 ]. Berries of the plant (2.5 and 5.0 mg/kg) also showed cardioprotective and antioxidant properties.…”

Section: Potential Role Of Solanum Nigrum In Post-...mentioning

confidence: 84%

Solanum nigrum L. in COVID-19 and post-COVID complications: a propitious candidate

et al. 2023

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COVID-19 is caused by severe acute respiratory syndrome coronavirus-2, SARS-CoV-2. COVID-19 has changed the world scenario and caused mortality around the globe. Patients who recovered from COVID-19 have shown neurological, psychological, renal, cardiovascular, pulmonary, and hematological complications. In some patients, complications lasted more than 6 months. However, significantly less attention has been given to post-COVID complications. Currently available drugs are used to tackle the complications, but new interventions must address the problem. Phytochemicals from natural sources have been evaluated in recent times to cure or alleviate COVID-19 symptoms. An edible plant, Solanum nigrum, could be therapeutic in treating COVID-19 as the AYUSH ministry of India prescribes it during the pandemic. S. nigrum demonstrates anti-inflammatory, immunomodulatory, and antiviral action to treat the SARS-CoV-2 infection and its post-complications. Different parts of the plant represent a reduction in proinflammatory cytokines and prevent multi-organ failure by protecting various organs (liver, kidney, heart, neuro, and lung). The review proposes the possible role of the plant S. nigrum in managing the symptoms of COVID-19 and its post-COVID complications based on in silico docking and pharmacological studies. Further systematic and experimental studies are required to validate our hypothesis.

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Section: Potential Role Of Solanum Nigrum In Post-...mentioning

confidence: 84%

Solanum nigrum L. in COVID-19 and post-COVID complications: a propitious candidate

et al. 2023

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Solanum aculeatissimum Jacq. Solanum nigrum L. Solanum surattense Burm. f. Solanaceae

Kunwar

Gautam

Dhami

et al. 2020

Ethnobotany of the Himalayas

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Solanum aculeatissimum Jacq. Solanum nigrum L. Solanum surattense Burm. f. Solanaceae

Kunwar

Gautam

Dhami

et al. 2021

Ethnobotany of Mountain Regions

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Cardio Protective Effect of <i>Solanum nigrum</i> Linn. in Isoproterenol Induced Myocardial Infarction in Rat

Abstract: Myocardial infarction is one of the highest confronting metabolic syndromes which cause morbidity and mortality across the world. Recently, the renewed interests in medicinal plants have certain preventive action in treatment of cardiovascular disorder.

Cited by 7 publications

References 2 publications

Solanum nigrum L. in COVID-19 and post-COVID complications: a propitious candidate

Solanum nigrum L. in COVID-19 and post-COVID complications: a propitious candidate

Solanum aculeatissimum Jacq. Solanum nigrum L. Solanum surattense Burm. f. Solanaceae

Solanum aculeatissimum Jacq. Solanum nigrum L. Solanum surattense Burm. f. Solanaceae

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