Cardiobacterium hominis prosthetic valve endocarditis: an infrequent infection

Abstract

A case of prosthetic aortic valve endocarditis due to Cardiobacterium hominis in a 67-year-old woman is described. The diagnosis was confirmed by a positive blood culture and echocardiographic detection of aortic valve vegetations. The patient underwent replacement of the valve with a homograft, and received antibiotics postoperatively. She remained well after 12 months.

Cardiobacterium hominis infective endocarditis: A literature review

“…Therefore, in some cases, the identification of C. hominis requires a significant period of time [2] , [6] , [13] . Our review revealed that there was a case in which the culture extended until 6 weeks to identify the organism [24] . Because of its fastidious and slow-growing nature, blood cultures should be continued for ≥14 days if a patient is suspected with IE [15] , [49] .…”

“…We searched the PubMed database to identify case reports of C. hominis IE and found 44 cases reported between January 2000 and June 2022 [1] , [6] , [7] , [8] , [9] , [10] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] . Herein, previously reported cases of C. hominis IE were reviewed and summarized.…”

Cardiobacterium hominis endocarditis associated with cerebral, renal, and splenic infarctions: A case report and review of the literature

“…C. hominis is also known to cause large friable vegetations complicated by systemic embolism [11] . Therefore, we reviewed cases of systemic embolism caused by C. hominis IE ( Table 2 ) [5] , [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] . 21 cases of C. hominis IE associated with embolism, including the present case, have been reported since 1980.…”

Cardiobacterium hominis and endocarditis. Rare but important clinical relevance

“…In our case the decision to replace rather than repair the valve was mainly due to size and site (anterior rather than posterior leafl et) of perforation and to the condition of the surrounding tissue. Most of the cases of CHIE in literature concern aortic valve [20,21] (in particular in case of bicupid valves) rather than mitral valve. Aneurysm of anterior mitral leafl et was the result of a valvulitis with subsequent formation of both granulation and scar tissue diplaced from the pressure.…”