Cardiothoracic ratio from postero-anterior chest radiographs: A simple, reproducible and independent marker of disease severity and outcome in adults with congenital heart disease

Dimopoulos, Konstantinos; Giannakoulas, George; Bendayán, Isaac Martínez; Liodakis, Emmanouil; Petraco, Ricardo; Diller, Gerhard‐Paul; Piepoli, Massimo F; Swan, Lorna; Mullen, Michael; Best, Nicky; Poole‐Wilson, Philip A.; Francis, Dárrel P.; Rubens, Michael B.; Gatzoulis, Michael Α.

doi:10.1016/j.ijcard.2011.10.125

Cited by 85 publications

(76 citation statements)

References 30 publications

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“…The standardization of this index for the tufted capuchin in the present research (0.55±0.04) showed normality values greater than those observed in humans (Dimopoulos et al 2013). Although it is a cardio thoracic ratio compatible with installed heart disease (Gustafsson et al 2003) and Solomon et al (2005), the animals studied did not present clinical or radiographic signs compatible with heart insufficiency to any degree.…”

Section: Discussioncontrasting

confidence: 45%

“…Gustafsson et al (2003) and Solomon et al (2005) reported that increase in the heart chambers reflects a range of pathological processes that can affect the cardiovascular function: hypertrophy, dilation and heart remodeling, established markers in acquired heart diseases. Dimopoulos et al (2013) demonstrated in humans that CTR greater than 0.55 is associated to cardiomegaly. These authors considered a CTR between 0.48 and 0.55 as a moderate heart increase index.…”

Section: Discussionmentioning

confidence: 99%

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Cardiothoracic ratio and vertebral heart size (VHS) to standardize the heart size of the tufted capuchin (Cebus apella Linnaeus, 1758) in computerized radiographic images

et al. 2015

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RESUMO.-[Índice cardiotorácico e vertebral heart size (VHS) para a padronização do tamanho cardíaco do macaco-prego (Cebus apella Linnaeus, 1758) em imagens radiográficas computadorizadas.] Para a avaliação do VHS e ICT foram utilizadas radiografias toráci-cas computadorizadas de 10 macacos-prego (05 machos e 05 fêmeas) clinicamente saudáveis, oriundos do Centro de Triagem de Animais Silvestres de São Luís-MA-CETAS. Foram tomadas radiografias em projeções laterolaterais e dorsoventrais, para cálculo do Vertebral Heart Scale (VHS) e Índice Cardiotorácico (ICT). O VHS evidenciou valores médios de 9,34±0,32v (machos) e 9,16±0,34v (fê-meas), não ocorrendo diferença estatística entre machos e fêmeas (p>0,05). O ICT evidenciou valores médios de 0,55±0,04 (machos) e de 0,52±0,03 (fêmeas), não sendo verificada diferença estatística entre sexos (p>0,05). Verificou-se correlação positiva entre VHS e ICT (r=0,78). Os diâmetros torácico e cardíaco demonstraram valores médios de 5,70±0,48cm e 3,16±0,40cm nos machos, The VHS and CTR were assessed using computerized thoracic radiographs of ten clinically healthy tufted capuchin monkeys (five males and five females) from the Wild Animal Screening Center in São Luís (Centro de Triagem de Animais Silvestres de São Luís-MA--CETAS). Radiographs were taken in laterolateral and dorsoventral projections to calculate the cardiothoracic ratio (VHS) and vertebral heart size (CTR). The VHS showed mean values of 9.34±0.32v (males) and 9.16±0.34v (females) and there was no statistical difference between males and females (p>0.05). The CTR showed mean values of 0.55±0.04 (males) and 0.52±0.03 (females) and there was no statistical difference between the sexes (p>0.05). There was positive correlation between VHS and CTR (r=0.78). The thoracic and heart diameters showed mean values of 5.70±0.48cm and 2.16±0.40cm in the males, respectively. In the females they measured 5.32±0.39cm and 2.94±0.32cm. There was no statistical difference between the sexes. Our results show that the high correlation found between VHS and CTR permitted the verification with similar clinical precision between the two methods to estimate alterations in the heart silhouette by radiographic examination of tufted capuchin, making it an easy technique to apply that can be considered in the investigation of heart problems for this wild species.

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Section: Discussioncontrasting

confidence: 45%

Section: Discussionmentioning

confidence: 99%

Cardiothoracic ratio and vertebral heart size (VHS) to standardize the heart size of the tufted capuchin (Cebus apella Linnaeus, 1758) in computerized radiographic images

et al. 2015

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“…Echocardiography and cardiac catheterisation are the mainstay of diagnosis, but important clues can be obtained on physical examination, electrocardiography, chest X-ray, computed tomography and magnetic resonance imaging [26][27][28]. Echocardiography may be deemed sufficient for establishing the presence of systemic levels of pulmonary arterial pressure in cyanotic patients with post-tricuspid defects and a low-velocity bidirectional shunt (Eisenmenger ventricular septal defect, atrioventricular septal defect and at times patent ductus arteriosus), for the purpose of avoiding invasive assessment.…”

Section: Diagnosis: Invasive and Non-invasivementioning

confidence: 99%

The spectrum of pulmonary arterial hypertension in adults with congenital heart disease: management from a physician and nurse specialist perspective

Dimopoulos

Harries

Parfitt

2017

J Congenit Heart Dis

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Congenital heart disease (CHD) is one of the most common causes of pulmonary arterial hypertension (PAH), with a prevalence nearing that of idiopathic PAH in registries. Despite similarities in pulmonary vascular pathology, PAH-CHD differs from idiopathic PAH and other types of PAH. In fact, PAH-CHD is a term that includes a wide spectrum of conditions and pathophysiologies, ranging from Eisenmenger syndrome to milder forms of PAH with systemic-topulmonary shunts, to those with previously repaired defects. Significant expertise in both CHD and PAH is required to manage these patients. We provide an overview of the modern management of the wide spectrum of PAH-CHD in adults, both from a physician and clinical nurse specialist perspective.

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“…Cardiomegaly, an independent marker of disease severity and outcome in patients with congenital heart disease, (12) is easily assessed in a postero-anterior chest X-ray (CXR). Signs of previous surgery including sternal wires from sternotomy and rib asymmetry from childhood thoracotomy can also be useful diagnostic features.…”

Section: Chest Radiographymentioning

confidence: 99%

Non-invasive imaging in congenital heart disease

Alonso‐Gonzalez

Swan

2017

SAHJ

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Cardiothoracic ratio from postero-anterior chest radiographs: A simple, reproducible and independent marker of disease severity and outcome in adults with congenital heart disease

Cited by 85 publications

References 30 publications

Cardiothoracic ratio and vertebral heart size (VHS) to standardize the heart size of the tufted capuchin (Cebus apella Linnaeus, 1758) in computerized radiographic images

Cardiothoracic ratio and vertebral heart size (VHS) to standardize the heart size of the tufted capuchin (Cebus apella Linnaeus, 1758) in computerized radiographic images

The spectrum of pulmonary arterial hypertension in adults with congenital heart disease: management from a physician and nurse specialist perspective

Non-invasive imaging in congenital heart disease

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