Cardiovascular comorbidities of pediatric psoriasis among hospitalized children in the United States

Kwa, Lauren; Kwa, Michael; Silverberg, Jonathan I.

doi:10.1016/j.jaad.2017.08.034

Cited by 32 publications

(42 citation statements)

References 16 publications

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“…In the current study, we found a higher prevalence of overweight/obesity in children with psoriasis (27.4%) than controls (12.4%) with OR 2.67, which are consistent with findings of the studies conducted by Kwa et al . (only obese) 7.4% versus 1.5%, Boccardi et al . (only overweight) 48.0% versus 27.0%, Zhu et al .…”

Section: Discussionmentioning

confidence: 90%

“…Only one child in the control group had hypertension. Similar findings were identified by Kwa et al ., 4.2% versus 1.2%, and Torres et al ., 10.0% versus 3.7% …”

Section: Discussionmentioning

confidence: 90%

“…The risk of diabetes occurring in children with psoriasis was 2.96‐fold. These findings are similar to findings of the study by Kwa et al ., 2.6% versus 0.5% with OR 2.90, and a meta‐analysis of Pietrzak et al ., which also found a higher concentration of blood glucose among children with psoriasis than controls …”

Section: Discussionmentioning

confidence: 95%

“…9 A study on American children found a higher prevalence of obesity, ª 2020 The International Society of Dermatology International Journal of Dermatology 2020, 59, 451-456 hypertension, and diabetes in the psoriasis group than in controls. 10 Augustin et al found a higher risk of dyslipidemia, obesity, hypertension, and diabetes in German children with psoriasis than the controls. 11 Mahe et al found a lower frequency of metabolic syndrome, obesity, diabetes, hypertension, and dyslipidemia in childhood-onset psoriasis than adult-onset psoriasis in France.…”

Section: Introductionmentioning

confidence: 98%

“…However, these studies were limited by inadequate sample size . A study on American children found a higher prevalence of obesity, hypertension, and diabetes in the psoriasis group than in controls . Augustin et al .…”

Section: Introductionmentioning

confidence: 99%

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Association of metabolic syndrome with pediatric psoriasis: a case‐control study in Kabul, Afghanistan

2020

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Background Limited studies have assessed the risk of metabolic syndrome in pediatric psoriasis. This study was aimed to investigate the association of obesity and metabolic syndrome with pediatric psoriasis in Afghanistan. Methods A case‐control study was conducted from March to December 2018 at the dermatology department of Maiwand Teaching Hospital in Kabul city. Participants were children aged less than 18 years; 113 children with psoriasis and 113 children without psoriasis were compared. Height, weight, waist circumference, and blood pressure were measured. Blood samples were taken following overnight fasting to test serum levels of glucose, triglyceride, cholesterol, and high‐density lipoprotein cholesterol. Analyses were done using Chi‐square test and independent t test. Odds ratio and 95% confidence interval were calculated. Results The mean age was 13.9 ± 3.7 and 13.4 ± 3.4 years in the psoriasis and control groups, respectively. Males comprised 54.9% of the psoriasis group and 41.6% of the control group. Family history of skin disorders was higher among children with psoriasis compared to the control group (23.0% vs. 13.7%; P < 0.001). Children with psoriasis were more likely to be overweight/obese (27.4% vs. 12.4%, OR = 2.67; P = 0.005), to have central adiposity with waist‐height ratio of 0.5 or greater (23% vs. 9.7%, OR = 2.77; P = 0.007), and to have metabolic syndrome (13.3% vs. 2.3%, OR = 5.23; P = 0.005). Conclusion The study revealed that children with psoriasis were more likely to have metabolic syndrome and cardiovascular risk factors compared to children without psoriasis.

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Section: Discussionmentioning

confidence: 90%

“…Only one child in the control group had hypertension. Similar findings were identified by Kwa et al ., 4.2% versus 1.2%, and Torres et al ., 10.0% versus 3.7% …”

Section: Discussionmentioning

confidence: 90%

Section: Discussionmentioning

confidence: 95%