ACOrUNCTtmE has been used in the Orient for over 2,000 years. 1,~ Recent reports have stimulated interest in this modality of treatment, but it is not widely accepted due to lack of well-controlled clinical studies ya Stimulation of acupuncture loci or acupoints can be provided in various ways including pressure, cupping, needling alone, needling with twirling, needling with electrostimulation, electrostimulation alone, and application of heat by various means such as moxa~ and electrocautery. Classical methods of acupuncture include: (1) needling alone, (2) needling with twirling, (3) needling with electrical stimulation, and (4) burning of moxa upon the skin (moxibustion). lo-17 Marked changes in the cardiovascular system have been observed following acupuncture in dogs under halothane anaesthesia. 18-2~ Moxibustion by electrocautery at Jen Chung (Go-26) produced greater changes in cardiovascular parameters than pressure alone, needling alone, needling with twirling or needling with electrical stimulation./s,~l,z2' There is evidence that the effects of acupuncture are mediated through the autonomic nervous system. :~,19 Since stimulation of the Jen Chung (Go-26) locus produced a consistent sympathomimetic effect in dogs under halothane anaesthesia, the ensuing study was formulated to determine if administration of the fl-adrenergic blocking agent propranolol would inhibit this effect. ~8.~9,-~,22 Moxibustion with electric cautery was selected as the means of stimulating Jen Chung (Go-26) since the cardiovascular response produced by moxibustion is greater than that observed following acupuncture performed by needles. 22 METHODS AND MATERIALS This study was performed in 34 random-source conditioned dogs in which an electromagnetic flow probe (Zepeda) had been implanted around the ascending aorta as previously described. '8,1'~,2',~.~4 After implantation, the dogs were observed for about ten days to ensure proper recovery and that the flow probes were well tolerated.