2013
DOI: 10.1016/j.ijcard.2012.05.123
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Cardiovascular events in a prehypertensive Chinese population: Four-year follow-up study

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Cited by 33 publications
(32 citation statements)
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“…Recent studies found an association between pre-hypertension and increased risk of Coronary Artery Disease [11,12]. Follow up studies also reported that prehypertension is an independent risk factor for cardiovascular and cerebrovascular diseases [13]. A recent meta-analysis reports that even lower range of prehypertension is associated with higher risk of cardiovascular disease (CVD) [14].…”
Section: Introductionmentioning
confidence: 99%
“…Recent studies found an association between pre-hypertension and increased risk of Coronary Artery Disease [11,12]. Follow up studies also reported that prehypertension is an independent risk factor for cardiovascular and cerebrovascular diseases [13]. A recent meta-analysis reports that even lower range of prehypertension is associated with higher risk of cardiovascular disease (CVD) [14].…”
Section: Introductionmentioning
confidence: 99%
“…1 Although the exact mechanisms involved in the causation of prehypertension have not yet been clearly explained, recent reports from our laboratory have demonstrated the association of sympathovagal imbalance (SVI) in the form of sympathetic overactivity and vagal withdrawal with prehypertension status in prehypertension. 2e4 We have reported that decreased vagal modulation of cardiac functions and decreased heart rate variability (HRV) are major CV risks in prehypertensives.…”
mentioning
confidence: 99%
“…12 However, to the best of our knowledge, no study has been conducted till date to assess the role of SVI in prediction of CV risks in prehypertension. As prehypertension is reported to be quite prevalent in younger age group, 1,9 in the present study, we have assessed CV and autonomic functions by HRV analysis, baroreflex sensitivity (BRS) assessed by blood pressure variability (BPV) monitoring, and conventional autonomic function tests (AFT) and analyzed the link of CV risks such as inflammation, insulin resistance, dyslipidemia, and oxidative stress to SVI in young prehypertensives.…”
mentioning
confidence: 99%
“…Hypertension plays a leading role in the cause of premature death and disability [12]. Furthermore, it is directly linked to the risk of developing cardiovascular diseases, cerebrovascular diseases, and chronic kidney diseases [13][14][15][16]. Studies reveal that 33% urban and 25% of Indians are hypertensive and only 1-10 th of rural and 1-5 th of urban are on control [17].…”
Section: Discussionmentioning
confidence: 99%