Cardiovascular Reflexes in Patients With Vascular Headache

Martín, R.; Ribera, Cristina; Moltò, J. M.; Ruíz, Carolina; Galiano, L; Matías-Guiu, J

doi:10.1111/j.1468-2982.1992.00360.x

Cited by 27 publications

(31 citation statements)

References 10 publications

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“…Since most studies addressing arterial function in migraineurs excluded subjects with comorbid vascular risk factors, other mechanisms can be hypothesized. The possible hypotheses include alterations in vessel wall structure in migraineurs as supported by the presence of impaired serum elastase activity [49], higher sympathetic tone [50,51], use of drugs such as triptans and ergot derivatives, or it may represent a primary alteration linked to the presence of migraine itself [52]. At the moment it is unknown whether the duration of migraine and the frequency and severity of the attacks has an impact on arterial stiffness.…”

Section: Discussionmentioning

confidence: 99%

Peripheral vascular dysfunction in migraine: a review

et al. 2013

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Numerous studies have indicated an increased risk of vascular disease among migraineurs. Alterations in endothelial and arterial function, which predispose to atherosclerosis and cardiovascular diseases, have been suggested as an important link between migraine and vascular disease. However, the available evidence is inconsistent. We aimed to review and summarize the published evidence about the peripheral vascular dysfunction of migraineurs.We systematically searched in BIOSIS, the Cochrane database, Embase, Google scholar, ISI Web of Science, and Medline to identify articles, published up to April 2013, evaluating the endothelial and arterial function of migraineurs.Several lines of evidence for vascular dysfunction were reported in migraineurs. Findings regarding endothelial function are particularly controversial since studies variously indicated the presence of endothelial dysfunction in migraineurs, the absence of any difference in endothelial function between migraineurs and non-migraineurs, and even an enhanced endothelial function in migraineurs. Reports on arterial function are more consistent and suggest that functional properties of large arteries are altered in migraineurs.Peripheral vascular function, particularly arterial function, is a promising non-invasive indicator of the vascular health of subjects with migraine. However, further targeted research is needed to understand whether altered arterial function explains the increased risk of vascular disease among patients with migraine.

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Section: Discussionmentioning

confidence: 99%

Peripheral vascular dysfunction in migraine: a review

et al. 2013

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“…(1991), who reported hyperthyroidism in five of 30 patients with chronic headache. A number of researchers have suggested an altered activity of the sympathetic nervous system in migraineurs (Sicuteri, 1967; Johnson, 1978; Martin et al. , 1992; Ferrari, 1993; Stronks et al.…”

Section: Discussionmentioning

confidence: 99%

Low headache prevalence amongst women with high TSH values

Hagen

Bjøro

Zwart

et al. 2001

Euro J of Neurology

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The aim of this large cross-sectional population-based study was to examine a possible positive or negative association between thyroid dysfunction and headache. Between 1995 and 1997, all 92 566 adults in Nord-Trøndelag County in Norway were invited to participate in a health survey. A total of 51 383 (56%) responded to a headache questionnaire, whereof thyroid-stimulating hormone (TSH) was measured in 28 058 individuals. These included 15 465 women and 8019 men above 40 years of age, 1767 randomly selected individuals between 20 and 40 years of age, and 2807 (97%) with thyroid dysfunction. Associations between thyroid dysfunction and headache were assessed in multivariate analyses, estimating prevalence odds ratios (OR) with 95% confidence intervals (CIs). High TSH values were associated with low prevalence of headache. This was most evident amongst women with no history of thyroid dysfunction. Amongst these, headache was less probable (OR=0.5, 95% CI 0.3-0.7) if TSH > or = 10 mU/l than in women with normal TSH (0.2-4 mU/l). In all age groups between 40 and 80 years, TSH was lower amongst headache sufferers, especially migraineurs, than in those without headache complaints.

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“…As in migraine, patients with CVS have several autonomic features such as antecedent aura, associated headaches, photophobia, and phonophobia during an episode and may also have underlying dysautonomia. Dysautonomia has been described in adults with migraine and children with CVS 5–11 . A recent study using a questionnaire in 21 patients, which included three children, revealed that CVS was associated with fibromyalgia, orthostatic intolerance, interstitial cystitis, functional dyspepsia, functional abdominal pain, and complex regional pain syndrome 12 …”

Section: Introductionmentioning

confidence: 99%