Cardiovascular responses to energy drinks in a healthy population: The C-energy study

Kozik, Teri M.; Shah, Sachin A; Bhattacharyya, Mouchumi; Franklin, Teresa T.; Connolly, Therese F; Chien, Walter W.; Charos, George; Pelter, Michele M.

doi:10.1016/j.ajem.2016.02.068

Cited by 43 publications

(27 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our findings are similar to another study (n=27), which used the same dose as ours and found a significant 6‐ms prolongation in QTc at 2 hours when compared with placebo . Further, in a noncontrolled study (n=14) using the same dose (2 cans) as in our study, 57% of participants had a QTc >500 ms post consumption . In contrast, a study by Brothers et al (n=15), comparing low‐ and moderate‐dose energy drinks, coffee, and water, found no changes in the QTc interval.…”

Section: Discussionsupporting

confidence: 89%

Randomized Controlled Trial of High‐Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters

Fletcher

Lacey

Aaron

et al. 2017

JAHA

View full text Add to dashboard Cite

BackgroundCaffeine in doses <400 mg is typically not considered arrhythmogenic, but little is known about the additional ingredients in energy drinks. We evaluated the ECG and blood pressure (BP) effects of high‐volume energy drink consumption compared with caffeine alone.Methods and ResultsThis was a randomized, double‐blind, controlled, crossover study in 18 young, healthy volunteers. Participants consumed either 946 mL (32 ounces) of energy drink or caffeinated control drink, both of which contained 320 mg of caffeine, separated by a 6‐day washout period. ECG, peripheral BP, and central BP measurements were obtained at baseline and 1, 2, 4, 6, and 24 hours post study drink consumption. The time‐matched, baseline‐adjusted changes were compared. The change in corrected QT interval from baseline in the energy drink arm was significantly higher than the caffeine arm at 2 hours (0.44±18.4 ms versus −10.4±14.8 ms, respectively; P=0.02). The QTc changes were not different at other time points. While both the energy drink and caffeine arms raised systolic BP in a similar fashion initially, the systolic BP was significantly higher at 6 hours when compared with the caffeine arm (4.72±4.67 mm Hg versus 0.83±6.09 mm Hg, respectively; P=0.01). Heart rate, diastolic BP, central systolic BP, and central diastolic BP showed no evidence of a difference between groups at any time point. Post energy drink, augmentation index was lower at 6 hours.ConclusionsThe corrected QT interval and systolic BP were significantly higher post high‐volume energy drink consumption when compared with caffeine alone. Larger clinical trials validating these findings and evaluation of noncaffeine ingredients within energy drinks are warranted.Clinical Trial Registration URL: http://www.clinicaltrials.gov. Unique identifier: NCT02023723.

show abstract

Section: Discussionsupporting

confidence: 89%

Randomized Controlled Trial of High‐Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters

Fletcher

Lacey

Aaron

et al. 2017

JAHA

View full text Add to dashboard Cite

show abstract

“…Numerous reports of the adverse effects of ED intake have described a variety of symptoms and affected organ systems, including tachycardia, hypertension, confusion, agitation, seizures, liver damage, kidney failure and cardiac dysfunction, with potential deadly outcomes [2, 5]. Recent studies have demonstrated significant haemodynamic changes in healthy young individuals following ED consumption, with elevated systolic and diastolic blood pressures, increased cardiac output and myocardial load, repolarization abnormalities and reduced cerebral blood flow velocity [6–8], as well as a significant increase in circulating catecholamines, reflecting sympathetic activation [8].…”

Section: Introductionmentioning

confidence: 99%

Consumption of energy drinks among adolescents in Norway: a cross-sectional study

et al. 2018

View full text Add to dashboard Cite

BackgroundEnergy drink (ED) consumption is increasing all over the world. We sought to describe the consumption of EDs among adolescents in Norway, and to explore the determinants of daily and high consumption.MethodsPopulation-based cross-sectional data were collected from a sample of 31,091 secondary school students in grade 8–13 aged 12–19 years. School grade, residency, socioeconomic status (SES), physical activity and leisure screen time were included in multiple regression analyses, in order to investigate their associations with daily and high (≥four times weekly) ED consumption.Results52.3% of the respondents were ED consumers and 3.5% were high consumers. Boys consumed twice as much ED as girls (boys: 36.3 ml/day, girls: 18.5 ml/day, geometric means), and the proportion of male high consumers was 3.7-times higher than that of females. The adjusted odd ratio (OR) of upper secondary school (grades 11–13, ages 15–19) students being high ED consumers were higher than for lower secondary school (grades 8–10, ages 12–15) students (OR 1.1(confidence interval (CI):1.0–1.3)), as well as higher for rural than urban residents (OR 1.3 (CI: 1.1–1.5)). Gradients for the increased ORs of being a high ED consumer were found for decreased SES, decreased frequency of physical activity and increased daily leisure screen time.ConclusionsMore than half of the respondents reported that they were ED consumers. Daily and high consumption were independently associated with male gender, physical inactivity, high leisure screen time, low socioeconomic status and rural residency.Electronic supplementary materialThe online version of this article (10.1186/s12889-018-6236-5) contains supplementary material, which is available to authorized users.

show abstract

“…In a recent study, Wassef et al found that energy drink consumption was an additional causative factor for tachycardia [32]. Previous studies have demonstrated increased systolic blood pressure, altered electrolytes, and resulted repolarization abnormalities as cardiovascular responses to energy drinks in healthy populations [33,34]. The consumption of carbonated sugar-sweetened beverages, even if it does not have immediate effects, is also linked to chronic health problems, including cardiovascular diseases, obesity, type 2 diabetes, non-alcoholic fatty liver disease, and gout [34,35].…”

Section: Discussionmentioning

confidence: 99%

Association between Internet Use Behavior and Palpitation among Adolescents: A Cross-Sectional Study of Middle School Children from Northwest Romania

Lazea

Popa

Varga³

2020

IJERPH

View full text Add to dashboard Cite

Purpose: The use of the internet is a tool and media literacy has become an essential skill among adolescents. Related to this behavior, some adolescents evoke cardiovascular effects. The purpose of this study was to explore a possible correlation between internet use behavior and occurrence of palpitations and related symptoms among a representative cohort of adolescents from the north-west region of Romania. Method: The study included students of seven middle schools from Northwest Romania. Participants completed an anonymous questionnaire consisting of 18 questions about internet use. Results: In total, 1147 students responded to the study. Mean duration of daily internet usage was 2.57 h during school time and 3.57 h during the holidays. A total of 77% of adolescents had more than one symptom related to internet use, and 11% of them reported palpitations and related symptoms. We found an independent relation between palpitation and urban background, palpitations and the internet usage time interval 20:00–24:00, and palpitations and tobacco smoking. Strong heartbeats were independently associated with the time interval 12:00–16:00, tobacco smoking, and energy drink consumption. Conclusion: In our cohort, the most important factors associated with the occurrence of palpitations and related symptoms were the timeframe of internet usage and smoking.

show abstract

Cardiovascular responses to energy drinks in a healthy population: The C-energy study

Cited by 43 publications

References 28 publications

Randomized Controlled Trial of High‐Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters

Randomized Controlled Trial of High‐Volume Energy Drink Versus Caffeine Consumption on ECG and Hemodynamic Parameters

Consumption of energy drinks among adolescents in Norway: a cross-sectional study

Association between Internet Use Behavior and Palpitation among Adolescents: A Cross-Sectional Study of Middle School Children from Northwest Romania

Contact Info

Product

Resources

About