Cardiovascular Risk and Psoriasis

Evaluation and treatment of metabolic syndrome and cardiovascular disease in adult patients with psoriasis

“…The stratification of cardiovascular risk is important as patients with CVD and psoriasis are likely to have worse outcomes. The presence of carotid atherosclerotic plaques has also been observed commonly in patients with psoriasis and psoriatic arthritis 3,12,14 . Furthermore, Ahlehoff et al.…”

“…assessed the prognosis of patients with previous myocardial infarction and concluded that the presence of psoriasis leads to a statistically significant worse prognosis 15 . Additionally, there is emerging evidence that severe psoriasis is not only associated with CV risk factors but also with worse left ventricular performance index even in the absence of cardiac diseases 3 …”

“…Recent studies have demonstrated a direct relationship between the severity of psoriasis and risk of developing CVD, major adverse cardiovascular events (MACE), and metabolic syndrome 2 . There is currently a debate about whether the severity of psoriasis is directly associated with the frequently evidenced reduction in coronary flow reserve 3,4 . Osto et al.…”

“…2 There is currently a debate about whether the severity of psoriasis is directly associated with the frequently evidenced reduction in coronary flow reserve. 3,4 Osto et al suggested that even in mild presentations of psoriasis, the sustained inflammatory state may contribute to microvascular dysfunction. 3,4 This concept is reinforced by Flammer and Ruschitzka's theory of "two plaques for one syndrome," as a reference to the similarity of the proinflammatory cytokines leading to psoriatic plaques and atherosclerotic plaques.…”

Acinetobacter baumannii and cardiac impairment. Increasingly important nosocomial pathogen

“…In his clinical history there was psoriasis, diabetes newly diagnosed, a history of chronic obstructive pulmonary bronchitis with chronic pulmonary heart disease and a history of being a former smoker [7][8][9][10][11][12][13][14][15][16].…”