2017
DOI: 10.1007/s11886-017-0873-7
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Cardiovascular Risk in Survivors of Cancer

Abstract: Research continues to show that cardiovascular disease is an important cause of morbidity and mortality in cancer survivors. Cardiotoxicity related to chemotherapy and radiotherapy accounts for part of this increased risk. There is emerging evidence that cancer and cardiovascular disease share a similar biology and risk factors. At present, there are several guidelines and consensus recommendations for the management of cardiovascular risk in cancer survivors. The evidence base is accumulating though additiona… Show more

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Cited by 15 publications
(9 citation statements)
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“…While advances in cancer screening and treatment have led to vast improvements in survival, cancer survivors now face an increased risk of cancer recurrence and second primary cancers [2]. Additionally, cancer survivors experience many other late and long-term effects of cancer and its treatment including increased risk for cardiovascular disease, [3,4] chronic health conditions, [5] and psychological effects [6].…”
Section: Introductionmentioning
confidence: 99%
“…While advances in cancer screening and treatment have led to vast improvements in survival, cancer survivors now face an increased risk of cancer recurrence and second primary cancers [2]. Additionally, cancer survivors experience many other late and long-term effects of cancer and its treatment including increased risk for cardiovascular disease, [3,4] chronic health conditions, [5] and psychological effects [6].…”
Section: Introductionmentioning
confidence: 99%
“…However, newer protocols limit the chemotherapy dosing and improve radiation accuracy, which has shown to decrease the acute clinically evident cardiovascular complications to less than 1% [ 122 ]. A greater risk has been registered in children who were facing pre-existing cardiovascular risk factors, hence the importance of early recognition of heart disease in cancer survivors [ 123 ]. It is estimated that as many one in eight CCS treated with anthracyclines and chest radiotherapy will experience a life-threatening cardiovascular event 30 years after the treatment of childhood cancer [ 124 ].…”
Section: Cardiotoxicity and Cardiomyopathymentioning
confidence: 99%
“…Chemotherapy -anthracyclines, trastuzumab, cyclophosphamide, 5-fluorouracil, angiogenesis drugs, thyroid kinases, etc. increase the risk of cardiovascular diseases, having a direct toxic effect on the myocardium [5,6].…”
Section: Introductionmentioning
confidence: 99%