CARE guidelines for case reports: explanation and elaboration document

Riley, David S.; Barber, Melissa; Kienle, Gunver S.; Aronson, Jeffrey K; Schoen-Angerer, Tido von; Tugwell, Peter; Kiene, Helmut; Helfand, Mark; Altman, Douglas G.; Sox, Harold C.; Werthmann, Paul G.; Moher, David; Rison, Richard A.; Shamseer, Larissa; Koch, Christian A.; Sun, Gordon H.; Hanaway, Patrick; Sudak, Nancy; Kaszkin-Bettag, Marietta; Carpenter, James E.; Gagnier, Joel

doi:10.1016/j.jclinepi.2017.04.026

Cited by 1,276 publications

(794 citation statements)

References 63 publications

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“…The protocol was approved by the Ethical Committee of the University of Naples Federico II (protocol number 347/16), and the patients signed a written informed consent form. This article was written following the CARE statement guidelines (Consensus‐based Clinical Case Reporting Guideline Development, Riley et al []).…”

Section: Case Presentationmentioning

confidence: 99%

Use of injectable platelet‐rich fibrin in the treatment of plasma cell mucositis of the oral cavity refractory to corticosteroid therapy: A case report

Gasparro

Adamo

Masucci

et al. 2019

Dermatologic Therapy

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Plasma cell mucositis (PCM) is a rare benign disease affecting adults characterized by an erythematous mucosa, an epithelial hyperplasia, and a dense submucosal infiltration of mainly mature plasma cells. PCM has been treated with topical, intralesional, and systemic corticosteroids, antibiotics, and topical cyclosporin with unreliable results and questionable benefits. Here, we present a case of PCM, refractory to previous treatments, treated with i‐PRF (injectable platelet‐rich fibrin) injections. The infiltrations were performed once a week for 2 months. There were no adverse reactions to the treatment. The pain gradually reduced until the score of zero at the fourth infiltration, and the patient remained free of pain during the whole study period. Clinically, we did not obtain a complete healing of the lesion, but a reduced perilesional inflammatory infiltrate was observed at a distance. Therefore, we can conclude that i‐PRF has been effective in the management of pain in PMC but does not result in complete healing of the disease.

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Section: Case Presentationmentioning

confidence: 99%

Use of injectable platelet‐rich fibrin in the treatment of plasma cell mucositis of the oral cavity refractory to corticosteroid therapy: A case report

Gasparro

Adamo

Masucci

et al. 2019

Dermatologic Therapy

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show abstract

“…Case reports comprise a significant proportion of the articles in many indexed medical journals. Case report volume, indexed on Embase and MEDLINE, increased by 45% from 49 918 in 2000 to 72 388 in 2010 5,6 . This amount of publication explains why it is important and pertinent to study the completeness and the proper writing of these articles.…”

Section: Introductionmentioning

confidence: 99%

“…Case report volume, indexed on Embase and MEDLINE, increased by 45% from 49 918 in 2000 to 72 388 in 2010. 5,6 This amount of publication explains why it is important and pertinent to study the completeness and the proper writing of these articles. It could be a potential and wide way to reduce "waste in research".…”

Section: Introductionmentioning

confidence: 99%

Completeness of reporting of case reports in high‐impact medical journals

Calvache

Vera-Montoya

Ordoñez

et al. 2020

Eur J Clin Investigation

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Introduction Case reports represent a relevant, timely and important study design in advancing medical scientific knowledge. They allow integration between clinical practice and clinical epidemiology. We aimed to assess the completeness of reporting (COR) of case reports published in high‐impact journals. We assessed the COR of case reports using the CARE guidelines. Materials and methods We selected three high‐impact journals and one journal specialized in publishing case reports, in which we included all published case reports from July to December 2017. Median COR score was calculated per study, and CORs were compared between journals with and without endorsement of CARE guidelines. Results One hundred and fourteen case reports were included. Overall median COR was 81%, IQR [63%‐96%]. Sections with the highest COR (84%‐100%) were patient information, clinical findings, therapeutic intervention, follow‐up and outcomes, discussion and informed consent. Sections with the lowest COR were title, keywords, timeline and patient perspective (2%‐34%). COR was higher in journals endorsing in comparison to those not endorsing CARE guidelines (77% vs 65%), respectively, median difference = −12% 95% CI [−16% to −7%]. Discussion Overall completeness of case reports in included journals is high especially for CARE endorsing and dedicated journals but reporting of some items could be improved. Ongoing and future evaluations of endorsement status of reporting guidelines in medical journals should be assessed to improve completeness and reduce waste of clinical research, including case reports.

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“…The authors thank Dr Helmut Kiene for revision of the manuscript. This case report was prepared following the CARE Guidelines …”

Section: Acknowledgmentsmentioning

confidence: 99%

Durable clinical remission of a skull metastasis under intralesional Viscum album extract therapy: Case report

Werthmann¹,

Huber

Kienle

2018

Head & Neck

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BackgroundSkull metastases are rare, they can eventually cause pain, and can invade the brain. Viscum album extracts (VAEs) are used as an adjuvant treatment in cancer.Methods and ResultsA 68‐year‐old patient with rectal cancer presented with lung metastases, and metastases to multiple bone sites, the chest wall, and the liver were later identified. Histological examination of one of the bone lesions revealed an additional thyroid carcinoma. An osteolytic parietal bone lesion progressed to a painful metastasis of the skull despite radiotherapy and chemotherapy. The VAEs were applied weekly into the metastasis, followed by pain relief and softening of the lesion. The lesion partially regressed (>50%) after 8 months of continued VAE treatment and remained stable for 2 years.ConclusionThis case shows a durable clinical remission of a skull metastasis under VAE. Further investigations of intratumoral VAE treatment seem worthwhile—especially in symptomatic skull metastases not responding to radiotherapy or systemic therapies.

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CARE guidelines for case reports: explanation and elaboration document

Cited by 1,276 publications

References 63 publications

Use of injectable platelet‐rich fibrin in the treatment of plasma cell mucositis of the oral cavity refractory to corticosteroid therapy: A case report

Use of injectable platelet‐rich fibrin in the treatment of plasma cell mucositis of the oral cavity refractory to corticosteroid therapy: A case report

Completeness of reporting of case reports in high‐impact medical journals

Durable clinical remission of a skull metastasis under intralesional Viscum album extract therapy: Case report

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