“…The studies showed seven different pharma ceutical forms of metronidazole: vaginal cream (12) , injectable (13) , powder (18) , tablets (19) , 1% saline solution (14) , 0.75% gel (4,16,20) and 0.80% gel (17) . The most used form of administration was the topical route in eight studies (80.0%) (4,12,(14)(15)(16)(17)(18)(19) and two studies used the systemic route (20.0%) (13,20) . The gel preparation at 0.75% was the most used and evidenced in three studies (30.0%) (4,16,20) .…”