Caribbean ciguatoxin profile in raw and cooked fish implicated in ciguatera

Abraham, Ann; Jester, Edward L.E.; Granade, Hudson R.; Plakas, Steven M.; Dickey, Robert

doi:10.1016/j.foodchem.2011.08.059

Cited by 66 publications

(73 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…LC-MS/MS is the method of choice used for the analysis of CTXs in different matrices: monk seals (Bottein et al, 2011), fish (Abraham et al, 2012;Lewis et al, 2009;Mak et al, 2013;Oshiro et al, 2010;Wong et al, 2014;Wu et al, 2011).…”

Section: Detection: Chemico-analytical Methodsmentioning

confidence: 99%

“…The toxins were extracted with MeOH under pressurized and warm conditions (1,500 psi, 75°C) and the final extract was in 50% aqueous MeOH. The solvents or mixtures of solvents used for the extraction of CTXs from fish flesh are acetone (Abraham et al, 2012;Caillaud et al, 2012;Oshiro et al, 2010), MeOH (Epelboin et al, 2014) or MeOH : n-hexane(3:1, v/v) (Lewis et al, 2009;Stewart et al, 2010;Wong et al, 2014).…”

Section: Extraction and Cleanupmentioning

confidence: 99%

“…Liquid-liquid partitioning steps using n-hexane and diethyl ether were used to remove the lipophilic interferences and to extract the toxins of interest, respectively, from blood samples (Bottein et al, 2011) or fish extracts (Abraham et al, 2012;Caillaud et al, 2012;Epelboin et al, 2014;Oshiro et al, 2010).…”

Section: Extraction and Cleanupmentioning

confidence: 99%

“…Regarding SPE cleanup, C18 and silica (Si) SPE cartridges were used consecutively or alone on extracts of different nature: monk seals livers (Bottein et al, 2011), fish flesh (Abraham et al, 2012;Lewis et al, 2009;Stewart et al, 2010;Wong et al, 2014;Wu et al, 2011) and blood samples from coral reef fishes (Mak et al, 2013).…”

Section: Extraction and Cleanupmentioning

confidence: 99%

See 3 more Smart Citations

Review and analysis of occurrence, exposure and toxicity of cyanobacteria toxins in food

Testai

Buratti

Funari

et al. 2016

EFS3

105

125

View full text Add to dashboard Cite

This report presents the extensive literature search conducted on 1) the occurrence of different cyanotoxins in food matrices; 2) the analytical methods for their detection; 3) their toxicological profile; 3) the environmental factors affecting toxicity of cyanobacterial population and 4) the combined effects of mixtures of cyanotoxins and other chemicals. It also includes a review of guidelines values or health-alert levels for cyanotoxins in food (or drinking water) adopted world-wide. The methodological aspects and the queries used in the extensive literature search, the collection and screening of retrieved papers and the inventory are briefly described in the report; all details are available in 3 supplementary appendices to this report. The analysis of collected papers indicated that most of them are focused on a single microcystin (MC) variant (MC-LR) out of the almost 100 MC known. Many studies on occurrence are affected by limited quality, due to analytical drawbacks in the detection methods and were not considered in the exposure assessment. Toxicity studies useful for the derivation of health based reference values are few, being many of them carried out using i.p. injection, which is poorly representative of actual human exposure. In addition, those toxicological studies carried out with poorly characterised cyanobacterial extracts or focused on single parameters, using a single dose, devoted to elucidation of mechanism of action, reporting qualitative description of effects were not used for data extraction. The relevant exposure scenarios are also described, although being the available data on exposure very limited, no definite conclusion on the health risks for the exposed population could be drawn. However, the possibility of risky exposure is evidenced for fish and shell-fish consumers and for blue-green algae supplements (BGAS) as well in relation to MC contamination. Finally, many data gaps were identified. © European Food Safety Authority, 2016Key words: Cyanobacteria, cyanotoxins, occurrence, toxicity, exposure, risk assessment, data gaps. Question number: EFSA-Q-2015-00141Correspondence:sc.secretariat@efsa.europa.eu Cyanotoxins in foodThe present document has been produced and adopted by the bodies identified above as author(s). This task has been carried out exclusively by the author(s) in the context of a contract between the European Food Safety Authority and the author(s), awarded following a tender procedure. The present document is published complying with the transparency principle to which the Authority is subject. It may not be considered as an output adopted by the Authority. The European Food Safety Authority reserves its rights, view and position as regards the issues addressed and the conclusions reached in the present document, without prejudice to the rights of the authors.www.efsa.europa.eu/publications 2 EFSA Supporting publication 2016:EN-998NDisclaimer: The present document has been produced and adopted by the bodies identified above as author(s). This task has b...

show abstract

Section: Detection: Chemico-analytical Methodsmentioning

confidence: 99%

Section: Extraction and Cleanupmentioning

confidence: 99%

Section: Extraction and Cleanupmentioning

confidence: 99%

Section: Extraction and Cleanupmentioning

confidence: 99%

See 2 more Smart Citations

Review and analysis of occurrence, exposure and toxicity of cyanobacteria toxins in food

Testai

Buratti

Funari

et al. 2016

EFS3

105

125

View full text Add to dashboard Cite

show abstract

“…Ciguatoxin is a colourless, odourless, heat stable, lipid-soluble polyether which is not destroyed by the cooking process 1 . Ciguatoxin is primarily produced by dinoflagellates of the genus Gambierdiscus.…”

Section: Ciguatera Fish Poisoning (Cfp) Occurs When Humans Ingest Fismentioning

confidence: 99%

Presumptive Case of Ciguatera Fish Poisoning in Mangalore, India

Rajeish¹,

Shekar²,

Madhushree³

et al. 2016

Current Science

View full text Add to dashboard Cite

Application of LANDSAT data and synoptic remote sensing to predictive models for prehistoric archaeological sites: an example from the Delaware coastal plain. Am. Antiq., 1986, 51, 572-588. 24. Oltean, I. A., Rajani, M. B. and Nalini, N. S., Archaeometallurgy in the Telangana region: a GIS approach in pioneering metallurgy: the origins of iron and steel making in the southern Indian subcontinent.

show abstract