Caryolane-type sesquiterpenes from Cirsium souliei

Syringin: A Phenylpropanoid Glycoside Compound in Cirsium brevicaule A. GRAY Root Modulates Adipogenesis

“…Some Cirsium species are used as edible and medicinal plants in traditional medicine, although other species are often considered as invasive weeds against which massive means of herbicidal control are deployed [ 7 , 8 ]. It is well known that Cirsium species contain a variety of natural products, and their main secondary metabolites include flavonoids and glycosides [ 9 , 10 ]. Many studies have reported that compounds from Cirsium species and their extracts show different biological activities, such as antioxidant, antidiabetic, anti-inflammatory, hepatoprotective, and anticancer activities [ 7 ].…”

“…Nonpolar crude extracts of C. pascuarense , and C. vulgare and C. ehrenbergii have been shown to confer antidiabetic and hepatoprotective activities, respectively [ 14 , 15 ]. In China, the roots or entire plants of more than ten Cirsium species ( C. japonicum , C. eriophoroideum , C. escuientum , C. griseum , C. lineare , C. maackii , C. pendulum , C. setosum , C. souliei , and C. valassovianum ) have been used as a folk medicine for various diseases [ 10 ]. Previous studies have investigated the antioxidant activities of the methanol and water extracts of the roots of C. japonicum , and also confirmed that both extracts have high phenolic and flavonoid contents and beneficial activities against diabetes [ 16 ].…”

Antiproliferative and Antibacterial Activities of Cirsium scabrum from Tunisia

“…The cytotoxic activity described in the literature for some Cirsium species is not only attributed to cycloartane-type triterpenoids. Other studies highlighted the cytotoxic potential of other types of compounds, for example, caryolane-type sesquiterpenes from Cirsium souliei [ 6 ] or a nor- α -tocopheroid ( α -tocospiro C) from Cirsium setosum [ 22 ]. We also isolated from the CSPE partition of Cirsium scabrum leaves two common triterpenoids lupeol and taraxasterol acetate.…”

“…The species is also frequently used as an emergency haemostatic for wounds [ 5 ]. The roots or the entire plants of more than ten species are used in China for the treatment of various ailments including hemorrhaging, jaundice, and gastrointestinal disorders [ 6 ]. According to literature, these traditional uses led to the consideration of the phytochemistry and the biological activities of some species.…”

“…Cirsium species contain a variety of natural products including flavonoids, phenolic acids, lignans, sesquiterpenoids, triterpenoids, sterols, alkaloids, acetylenes, polyacetylenes, hydrocarbons, and a few other compounds [ 7 ]. Flavonoids and their glycosides are the main secondary metabolites of Cirsium species [ 6 ]. The compounds isolated from Cirsium species and extracts show many different biological activities including antimicrobial, antioxidant, antidiabetic, anti-inflammatory, vasorelaxant, astringent, hepatoprotective, and anticancer activities [ 8 ].…”