Case 2

Comparison of Lesion Improvement in Lupoid Leishmaniasis Patients with Two Treatment Approaches

“…22 This chronic condition typically follows the acute form of CL and in the majority of cases is a complication of L. tropica in Old World leishmaniasis. 2 Although CL is self-limiting, if the lupoid form is left untreated, it would progress and lead to large scars; hence, disfigurement results, and the long duration of this requires an effective treatment. 23 As there is no standard treatment for this form of leishmaniasis, it might require prolonged courses of treatment or adjuvant therapy.…”

“…1 This chronic condition typically follows an acute form of CL, and in the majority of cases, Leishmania tropica is the causative agent. 1,2 Lupoid leishmaniasis is endemic in the Middle East and Afghanistan, with a reported incidence of 0.5 to 6.2% among all CL cases. 3 In Iran, the city of Mashhad, the capital of Khorasan Razavi province, is one of the endemic areas of CL, and more than 90% of cases are due to L. tropica.…”

“…1 This chronic condition typically follows an acute form of CL, and in the majority of cases, Leishmania tropica is the causative agent. 1,2…”

Case Report: Lupoid cutaneous leishmaniasis mimicking verruca plana

“…This clinical presentation with a chronic course develops after acute CL infection. In this clinical form, papulonodular lesions of granulomatous and lupoid character are seen 1–2 years after the acute lesion is healed 4 . Although there is an immune response against parasites in lupoid CL, the immune system is unable to remove the parasites altogether and thus the chronic granulomatous response continues for a long time 6 .…”

“…Lupoid CL is one of the more rarely seen forms of CL 4 . The incidence of lupoid CL has been reported to be 0.5 to 6.2% 5 .…”