Case-Control Study of Neuroepithelial Tumors in Rochester, Minnesota, 1950–1977

Mb, Codd; Lt, Kurland; Wm, O'Fallon; Cm, Beard; Tl, Cascino

doi:10.1159/000110748

Cited by 10 publications

(4 citation statements)

References 23 publications

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“…The intracranial meningioma incidence increases with patient age, ranging from 0.3 per 100,000 in childhood to 8.4 per 100,000 in the elderly, accounting for near 30% of incidental tumors found at autopsy [30][31] .…”

Section: Discussionmentioning

confidence: 99%

Computed tomography scan of the head in patients with migraine or tension-type headache

Valênça

Valença

Menezes³

2002

Arq. Neuro-Psiquiatr.

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-A retrospective study was performed in order to evaluate the frequency of abnormalities found by computed tomography (CT) scan of the head in 78 patients with migraine or tension-type headache. In the present study CT scan was normal in 61.5% of the patients with migraine or tension-type headache. A number of abnormalities were encountered in more than one third of the patients studied, including inflammatory sinus disease (19.2%), cysticercosis (3.9%), unruptuted cerebral aneurysm (2.6%), basilar impression (2.6%), intracranial lipoma (2.6%), arachnoid cyst (2.6%), empty sella (2.6%), intracranial neoplasm (2.6%), and others (2.6%). None of these lesions were symptomatic or responsible by the headache picture, therefore, considered incidental findings. In conclusion, the fortuitous encounter of some abnormalities on CT scan of the head is often higher than what we could predict in patients suffering migraine or tension-type headache. We briefly discuss clinical, epidemiologic, and practical management of some of the abnormalities detected by CT scan as well as the indication to request a neuroimaging investigation.KEY WORDS: headache, migraine, tension-type, CT scan, basilar impression, cysticercosis. T T T T Tomografia computadorizada do crânio em pacientes com migrânea ou cefaléia tensional omografia computadorizada do crânio em pacientes com migrânea ou cefaléia tensional omografia computadorizada do crânio em pacientes com migrânea ou cefaléia tensional omografia computadorizada do crânio em pacientes com migrânea ou cefaléia tensional omografia computadorizada do crânio em pacientes com migrânea ou cefaléia tensional RESUMO -Um estudo retrospectivo foi realizado visando avaliar a frequência de anormalidades encontradas durante a realização de estudo por tomografia computadorizada (TC) em 78 pacientes com migrânea ou cefaléia do tipo tensional. A TC foi normal em 61,5% dos pacientes examinados. Em um terço dos pacientes estudados foram detectadas anormalidades, como doença inflamatória dos seios paranasais (19,2%), cisticercose (3,9%), aneurisma cerebral não-roto (2,6%), impressão basilar (2,6%), lipoma intracraniano (2,6%), cisto aracnoideo (2,6%), sela vazia (2,6%), neoplasia intracraniana (2,6%) e outras afecções (2,6%). Nenhuma destas lesões era sintomática (achado incidental). Concluindo, o encontro fortuito de algumas anormalidades na TC é frequentemente mais elevado do que se prediz em pacientes com cefaléia primária. Nós discutimos brevemente alguns aspectos clínicos, epidemiológicos e da conduta terapêutica-cirúrgica sobre algumas das anomalias diagnosticadas pela TC. Também levantamos, ou questionamos, aspectos éticos que determinam o limite entre o direito do paciente e o direito do médico em afirmar que um indivíduo com dor de cabeça não é portador de lesão intracraniana, baseado na história clínica e no exame físico do paciente.

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Section: Discussionmentioning

confidence: 99%

Computed tomography scan of the head in patients with migraine or tension-type headache

Valênça

Valença

Menezes³

2002

Arq. Neuro-Psiquiatr.

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“…Case-control studies that compared controls with adult glioma patients who had a history of head injury requiring medical attention found no evidence of an association (ORs range from 0.7 to 1.3; Wrensch et al, 2000b). Somewhat higher relative risks have been reported when any head injuries are considered (Ahlbom et al, 1986;Burch et al, 1987;Choi et al, 1970;Codd et al, 1990;Preston-Martin et al, 1989;Ryan et al, 1992;Schlehofer et al, 1992), suggesting the possibility that cases may have been more likely to recall minor head injuries than controls. There has been more evidence of a possible link between head injuries and meningiomas or other brain tumors, such as acoustic neuromas (Inskip et al, 1995, Preston-Martin andMack, 1996), but casecontrol reporting differences might explain the ndings.…”

Section: Trauma and Head Injurymentioning

confidence: 99%

Epidemiology of primary brain tumors: Current concepts and review of the literature

Wrensch¹,

Minn²,

Chew³

et al. 2002

Neuro-Oncology

663

240

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The purpose of this review is to provide a sufficiently detailed perspective on epidemiologic studies of primary brain tumors to encourage multidisciplinary etiologic and prognostic studies among surgeons, neuro-oncologists, epidemiologists, and molecular scientists. Molecular tumor markers that predict survival and treatment response are being identified with hope of even greater gains in this area from emerging array technologies. Regarding risk factors, studies of inherited susceptibility and constitutive polymorphisms in genes pertinent to carcinogenesis (for example, DNA repair and detoxification genes and mutagen sensitivity) have revealed provocative findings. Inverse associations of the history of allergies with glioma risk observed in 3 large studies and reports of inverse associations of glioma with common infections suggest a possible role of immune factors in glioma genesis or progression. Studies continue to suggest that brain tumors might result from workplace, dietary, and other personal and residential exposures, but studies of cell phone use and power frequency electromagnetic fields have found little to support a causal connection with brain tumors; caveats remain. The only proven causes of brain tumors (that is, rare hereditary syndromes, therapeutic radiation, and immune suppression giving rise to brain lymphomas) account for a small proportion of cases. Progress in understanding primary brain tumors might result from studies of well-defined histologic and molecular tumor types incorporating assessment of potentially relevant information on subject susceptibility and environmental and noninherited endogenous factors (viruses, radiation, and carcinogenic or protective chemical exposures through diet, workplace, oxidative metabolism, or other sources). Such studies will require the cooperation of researchers from many disciplines.

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Section: Trauma and Head Injurymentioning

confidence: 99%

Epidemiology of primary brain tumors: Current concepts and review of the literature

Wrensch¹,

Minn²,

Chew³

et al. 2002

Neuro-Oncol

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Neuro-OncologyThe purpose of this review is to provide a suf ciently detailed perspective on epidemiologic studies of primary brain tumors to encourage multidisciplinary etiologic and prognostic studies among surgeons, neuro-oncologists, epidemiologists, and molecular scientists. Molecular tumor markers that predict survival and treatment response are being identi ed with hope of even greater gains in this area from emerging array technologies. Regarding risk factors, studies of inherited susceptibility and constitutive polymorphisms in genes pertinent to carcinogenesis (for example, DNA repair and detoxi cation genes and mutagen sensitivity) have revealed provocative ndings. Inverse associations of the history of allergies with glioma risk observed in 3 large studies and reports of inverse associations of glioma with common infections suggest a possible role of immune factors in glioma genesis or progression. Studies continue to suggest that brain tumors might result from workplace, dietary, and other personal and residential exposures, but studies of cell phone use and power frequency electromagnetic elds have found little to support a causal connection with brain tumors; caveats remain. The only proven causes of brain tumors (that is, rare hereditary syndromes, therapeutic radiation, and immune suppression giving rise to brain lymphomas) account for a small proportion of cases. Progress in understanding primary brain tumors might result from studies of well-de ned histologic and molecular tumor types incorporating assessment of potentially relevant information on subject susceptibility and environmental and noninherited endogenous factors (viruses, radiation, and carcinogenic or protective chemical exposures through diet, workplace, oxidative metabolism, or other sources). Such studies will require the cooperation of researchers from many disciplines. Neuro-Oncology 4, 278-299, 2002 (Posted to Neuro-Oncology [serial online], Doc. 02-011, August 27, 2002 P rimary malignant or benign brain tumors were estimated to be newly diagnosed in about 35,519 Americans in 2001 (CBTRUS, 2000. Epidemiologic studies enhance our understanding of this heterogeneous group of diseases in 2 ways. Descriptive studies characterize the incidence of brain tumors and the mortality and survival rates associated with them with respect to histologic tumor type and demographic characteristics of patients affected, such as their age, sex, and geographic region. Analytic epidemiologic studies either compare the risk of brain tumors in people with and without certain characteristics (cohort studies) or compare the histories of people with and without brain tumors (case-control studies) to provide information on a wide range of possible risk factors, including diet, smoking, alcohol, occupation and industry, exposure to ionizing or nonionizing radiation, infections, allergies, head trauma, family history, and inherited polymorphisms in genes related to carcinogen metabolism, oxidative metabolism, and DNA repair. Because of the relative ra...

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Case-Control Study of Neuroepithelial Tumors in Rochester, Minnesota, 1950–1977

Cited by 10 publications

References 23 publications

Computed tomography scan of the head in patients with migraine or tension-type headache

Computed tomography scan of the head in patients with migraine or tension-type headache

Epidemiology of primary brain tumors: Current concepts and review of the literature

Epidemiology of primary brain tumors: Current concepts and review of the literature

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