Case of Budd–Chiari syndrome 3 months after vaginal delivery

Hiroe, Sasaki; Itoh, Hiroaki; Matsumoto, Hisanori; Takahasi, Syhugen; Sato, Yukiyasu; Yamada, Shigetoshi; Okagaki, Atsuhiko; Kuzushita, Noriyoshi; Ban, Chiaki

doi:10.1111/j.1447-0756.2008.00893.x

Cited by 7 publications

(3 citation statements)

References 21 publications

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“…Unlike COC formulations, spironolactone seems to improve the thrombotic profile because aldosterone is known to be prothrombotic. Two individual case studies report the successful use of spironolactone-based treatment for Budd-Chiari syndrome in one patient with protein C deficiency and portal vein thrombosis in another patient with hepatitis B-related chronic liver disease (Hiroe et al, 2008, Kumar et al, 2011, Struthers and MacDonald, 2004). …”

Section: Spironolactonementioning

confidence: 99%

A Review of hormone-based therapies to treat adult acne vulgaris in women

Trivedi

Shinkai

Murase

2017

International Journal of Women's Dermatology

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Hormone-based therapies including combined oral contraceptive medications and spironolactone are considered effective therapies to treat adult acne in women. Our objective is to provide a concise and comprehensive overview of the types of hormonal therapy that are available to treat acne and comment on their efficacy and safety profiles for clinical practice. A systematic search using the PubMed Database was conducted to yield 36 relevant studies for inclusion in the review and several conclusions were drawn from the literature.Treatment with oral contraceptive pills leads to significant reductions in lesion counts across all lesion types compared with placebo. There were no consistent differences in efficacy between the different combined oral contraceptive formulations. In terms of risk, oral contraceptive pill users had three-times increased odds of venous thromboembolism versus non-users according to a recent meta-analysis (95% confidence interval 2.46-2.59). Data on oral contraceptive pill use and breast cancer risk are conflicting but individual patient risk factors and histories should be discussed and considered when prescribing these medications. However, use of these medications does confer measurable protection from endometrial and ovarian cancer. Spironolactone was also shown to be an effective alternative treatment with good tolerability.Combined oral contraceptive medications and spironolactone as adjuvant and monotherapies are safe and effective to treat women with adult acne. However, appropriate clinical examinations, screening, and individual risk assessments particularly for venous thromboembolism risk must be conducted prior to initiating therapy.

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Section: Spironolactonementioning

confidence: 99%

A Review of hormone-based therapies to treat adult acne vulgaris in women

Trivedi

Shinkai

Murase

2017

International Journal of Women's Dermatology

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“…These results signify that our patient responded well to anticoagulant therapy. However, the delay of initiation of the treatment might have led to Budd-Chiari syndrome, the most severe complication of protein C deficiency, because thrombosis extended to the level of the diagram in the second CT. [5] Laboratory tests and physical examination excluded leg ulcers caused by venous valve dysfunction, artheriosclerosis, arterial embolism, arteritis, and phlebitis. Although some patients with protein C deficiency develop warfarin induced necrosis, our patient did not.…”

Section: Sirmentioning

confidence: 99%

Edema and ulcers on the legs and dilated abdominal veins caused by thromboembolism of inferior vena cava in a patient with protein C deficiency

Kawano¹,

Ohata²,

Ono³

et al. 2013

Indian J Dermatol Venereol Leprol

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“…22 Most BCS cases occurred in patients with other risk factors for thrombosis than pregnancy. [23][24][25][26][27][28][29] In particular, women with protein S deficiency seem at higher risk for BCS during pregnancy. 22 This may be due to the previously described decrease in functional levels of this protein during pregnancy.…”

Section: Is Pregnancy a Risk Factor For Budd-chiari Syndrome?mentioning

confidence: 99%

Pregnancy and Vascular Liver Disease

Bissonnette

Durand

Raucourt

et al. 2015

Journal of Clinical and Experimental Hepatology

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Vascular disorders of the liver frequently affect women of childbearing age. Pregnancy and the postpartum are prothrombotic states. Pregnancy seems to be a trigger for Budd-Chiari syndrome in patients with an underlying prothrombotic disorder. Whether pregnancy is a risk factor for other vascular liver disorders is unknown. In women with a known vascular liver disorder and a desire for pregnancy, stabilisation of the liver disease, including the use of a portal decompressive procedure when indicated, should be reached prior to conception. The presence of esophageal varices should be screened and adequate prophylaxis of bleeding applied in a manner similar to what is recommended for patients with cirrhosis. Most women likely benefit from anticoagulation during pregnancy and the postpartum. Labor and delivery are best managed by a multidisciplinary team with experience in this situation. Assisted vaginal delivery is the preferred mode of delivery. Although the risk of miscarriage and premature birth is heightened, current management of these diseases makes it very likely to see the birth of a live baby when pregnancy reaches 20 weeks of gestation.

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Case of Budd–Chiari syndrome 3 months after vaginal delivery

Cited by 7 publications

References 21 publications

A Review of hormone-based therapies to treat adult acne vulgaris in women

A Review of hormone-based therapies to treat adult acne vulgaris in women

Edema and ulcers on the legs and dilated abdominal veins caused by thromboembolism of inferior vena cava in a patient with protein C deficiency

Pregnancy and Vascular Liver Disease

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