Case of minocycline‐effective confluent and reticulated papillomatosis with unusual location on forehead

Kim, Byung Soo; Lim, Hyun Jung; Kim, Ho Youn; Lee, Weon Ju; Lee, Seok‐Jong; Kim, Do Won

doi:10.1111/j.1346-8138.2009.00634.x

Cited by 10 publications

(3 citation statements)

References 14 publications

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“…There was one case report of CRP resistant to treatment with erythromycin that resolved with minocycline 40. The authors proposed that macrolides, such as azithromycin, have a much safer side effect profile and are pregnancy category B drugs.…”

Section: Treatmentmentioning

confidence: 99%

Confluent and reticulated papillomatosis: diagnostic and treatment challenges

Lim¹,

Tey²,

Chong³

2016

CCID

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Confluent and reticulated papillomatosis (CRP) of Gougerot and Carteaud was first typified in 1927. With the help of electron microscopy, it has been elucidated that CRP arises due to aberrant keratinization. However, till date, there is no clear consensus on the etiologic trigger for CRP. Prevailing postulates include a bacterial trigger by Dietzia papillomatosis (type strain N 1280T), an exaggerated cutaneous response to Malassezia furfur, an endocrine basis stemming from insulin resistance, ultraviolet light-induced epidermal change, amyloid deposition, and a loss-of-function mutation in keratin 16. CRP typically presents as asymptomatic hyperpigmented papules and plaques with peripheral reticulation over the nape, axillae, upper chest, and upper back, occasionally with extension superior to the forehead and inferior to the pubic region. Dermoscopy may be used in the evaluation of CRP, but its diagnosis is made on clinical grounds given its nonspecific histopathological findings. Although successful treatment with topical keratolytics, retinoids, or antifungals has been reported, antibiotics, such as minocycline, at anti-inflammatory doses have emerged as a preferred therapeutic option. In this article, we review the diagnostic considerations in CRP and its therapeutic options.

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Section: Treatmentmentioning

confidence: 99%

Confluent and reticulated papillomatosis: diagnostic and treatment challenges

Lim¹,

Tey²,

Chong³

2016

CCID

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“…13 Other oral treatment methods for CRP have been cited in the literature, including clarithromycin and erythromycin. 14,15 Topical treatments have been reported for use in the treatment of CRP, including retinoids, tazarotene, urea, calcipotriol, and tacrolimus. 16,17,18,19,20 A limitation in using topical treatment is the inability to reach the affected area for application, especially if CRP is located on the back.…”

Section: Skinmentioning

confidence: 99%

Successful Treatment of Confluent and Reticulated Papillomatosis with Minocycline Topical 4% Foam

Lateef¹,

Kraish

Lateef³

2022

J of Skin

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Confluent and reticulated papillomatosis of Gougerot and Carteaud (CRP) is a rare dermatosis with many proposed etiologies. Patients typically present with hyperpigmented papules on areas such as their back, chest, abdomen, and axilla which coalesce centrally and form reticular patterns peripherally. CRP is typically recalcitrant to therapy, making it difficult to treat. We report a case of a middle-aged Black woman with a rash on the center of her chest, extending beneath her inframammary folds. The patient was diagnosed with CRP clinically. Due to her concerns regarding oral antibiotics, she was placed on minocycline topical 4% foam for one month. Concluding her therapy, we observed a complete resolution of plaques with residual hyperpigmentation. To date, this is the first report in the literature on the usage of topical minocycline for the treatment of CRP.

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“…Lesions typically begin as hyperkeratotic small papules (1-2 mm) which enlarge and coalesce (4-5 mm) to form grayish brown papules and plaques in a confluent pattern centrally (on the midline region) and with a reticular pattern peripherally. Commonly, it begins on the skin of the intermammary or epigastric region, spreading over a period of weeks or months to axillae, groin, face, neck, arms, trunk, cheeks, pubic area, interscapular region, shoulders, the proximal extremities, and forehead [1][2][3][4] . The mucus membranes are spared.…”

mentioning

confidence: 99%

A Teen Lesion of Confluent and Reticulated Papillomatosis ( CRP )

Ubaidi¹

2015

BMB

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A nineteen-year-old Bahraini male with a diagnosis of confluent and reticulated papillomatosis received numerous treatments with minimal response. The patient responded favorably to the treatment of oral minocycline for 6 weeks plus topical mupirocin and has remained since then in remission. Confluent and reticulated papillomatosis (CRP) is a rare chronic skin disease which usually affects adolescents. The patient seeks treatment only for cosmetic reasons.The diagnosis of CRP should be considered if the lesion does not respond to antifungal treatment.

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Case of minocycline‐effective confluent and reticulated papillomatosis with unusual location on forehead

Cited by 10 publications

References 14 publications

Confluent and reticulated papillomatosis: diagnostic and treatment challenges

Confluent and reticulated papillomatosis: diagnostic and treatment challenges

Successful Treatment of Confluent and Reticulated Papillomatosis with Minocycline Topical 4% Foam

A Teen Lesion of Confluent and Reticulated Papillomatosis ( CRP )

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