Understanding the function of piriformis muscle plays an important role in the procedures of diagnosis and treatment in the piriformis syndrome which is observed as a result of the variations, hypertrophy, or strain of the muscle. Making the differential diagnosis with the anamnesis and physical examination is important in the oftenmisdiagnosed piriformis syndrome. At this point, the functional anatomy of the muscle gains importance. In our study, we tried by performing a literature search and examining anatomy textbooks to compile all the functions of this muscle whose function is defined in various ways. In this regard, we hope this study can be used clinically as a guide for identifying movements that can cause pathology, taking precautions against such scenarios and for muscle test, stretching and strengthening exercises for the muscle.