Case Report: Ductal Carcinoma<i>In Situ</i>in the Male Breast

Chern, Joshua J.; Liao, Lydia; Baraldi, R.; Tinney, Elizabeth; Hendershott, Karen; Germaine, Pauline

doi:10.1155/2012/532527

Cited by 6 publications

(8 citation statements)

References 3 publications

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“…The radiological evaluation of the male breast is not standardized, the mammography is done first and is followed by ultrasound (1,3).…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, the DCIS of the male is expected to have a good prognosis with simple mastectomy only and no axillary sentinel node biopsy or chemotherapy is needed as in female patients. Meanwhile, some authors actually recommend the use of sentinel lymph node systematically (1,4). Radiotherapy may be recommended for a male patient with DCIS treated by lumpectomy or patients with involved margins for reducing the local recurrence.…”

Section: Discussionmentioning

confidence: 99%

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Pure Ductal Carcinoma in Situ in The Male Breast: A Rare Entity

Sakhri

Jaïdane

Bouhani

et al. 2020

Eur J Breast Health

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Pure Ductal carcinoma in situ (DCIS) of the man is extremely rare. The incidence is approximately 1% of all malignancies in men and 5% to 7% of male breast cancer (1). It is usually associated with invasive carcinoma. We reported three cases on DCIS in men. The aim of our study is to further emphasize the importance of this disease for men and to evaluate the management of this rare tumor. Case PresentationsCase 1 A 58-year old man consulted for a left breast mass that has been evolving for 3 months. There was no remarkable personal history or family history of breast's disease. He had a remarkable history of smoking with 38 packages per year. On physical examination, we found a mobile, well-defined mass, measuring 20 mm × 20 mm without axillary lymph node. The right breast was unremarkable. Mammography and ultrasound showed a circumscribed nodule without calcifications in the left breast. This was considered as ACR 3 of the classification of the American College of Radiology (ACR) (Figure 1). We performed a core needle biopsy. The histological findings showed a DCIS. The patient underwent a mastectomy with sentinel node. Macroscopically, the tumor was greyish to white and measured 17 mm in its greater axis. The definitive histopathological assessments showed DCIS with papillary and cribriform patterns (Figure 2). The nuclear grade was intermediate, and there was no necrosis. Cells were polarized. The margins were free, with a clearance of 15 mm. No invasive cancer was present. The nuclear grade was I of Van Nuys. Van Nuys Prognostic Index score (VNPI) was 6 (Table 1). Sentinel lymph node sampling brought back three lymph nodes which were all negative. The immunohistochemical examination of estrogen (ER) and progesterone (PR) receptors were negative for both. The patient was noted to be doing well until now, and he is regularly followed up, with a total duration of follow-up of 10 years.A written informed consent was obtained from the patient.

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“…The radiological evaluation of the male breast is not standardized, the mammography is done first and is followed by ultrasound (1,3).…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Pure Ductal Carcinoma in Situ in The Male Breast: A Rare Entity

Sakhri

Jaïdane

Bouhani

et al. 2020

Eur J Breast Health

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“… 10 In previous studies of invasive breast cancer in men, a papillary histologic subtype was rare. 17 , 23 Therefore, Cherrn et al 24 suggest that papillary lesions in males are more likely to expand and remain in situ than other subtypes.…”

Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging findings of high-grade ductal carcinoma in situ of the male breast: A case report

Reinhardt

Mathys

Reinecke

et al. 2018

SAGE Open Medical Case Reports

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Ductal carcinoma in situ in men is incredibly rare and detection by conventional mammography and ultrasound is often challenging. We report an unusual case of a 50-year-old male, with no family history of breast cancer, who presented with an 8-year history of left-sided breast pain and recurrent bloody nipple discharge without any significant suspicious imaging features in mammography and targeted high-resolution ultrasound. Breast magnetic resonance imaging was performed as an adjunct modality. Magnetic resonance imaging findings revealed a suspicious retroareolar non-mass abnormality of segmental, linear and dendritic pattern, which was highly suspicious for a ductal carcinoma in situ. Stereotactic guided biopsy and subsequent mastectomy were consistent with pure high-grade ductal carcinoma in situ of the left breast. Overall, this case highlights the challenges in diagnosing ductal carcinoma in situ in men and demonstrates the importance for further investigating clinical suspicions of the male breast.

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“…[ 61 ] It can be associated with gynecomastia, and clinically presents as a palpable retroareolar mass, typically associated with nipple discharge, and usually discovered at both advanced stage, and late age in men compared to women. [ 62 , 63 ] In men, DCIS arises as a result of atypical proliferation of epithelial cells of the breast duct. [ 64 , 65 ] Thirty to fifty percent of all male and female patients with DCIS develop invasive cancer in the following 10–20 years.…”

Section: Classification Of Male Breast Lesionsmentioning

confidence: 99%

“…[ 64 ] The most common histopathological DCIS subtypes are papillary and cribriform, with or without classifications. [ 61 , 62 , 66 ]…”

Section: Classification Of Male Breast Lesionsmentioning

confidence: 99%

Unusual Male Breast Lesions

AlSharif

Alshamrani

Scaranelo

et al. 2021

JCIS

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Most of male breast masses are benign with gynecomastia being the most common entity encountered. Primary male breast cancer accounts for less than 1% of the total number of breast cancer. Male breast can be affected by a variety of conditions affecting the female breast with less frequency due to the lack of hormonal influence and consequent glandular sub-development. Imaging features of male breast masses are quite similar to the female breast. Therefore, using the knowledge of the female breast and applying it may help in the diagnosis and management of male breast abnormalities. In this article, we aim to review a variety of unusual male breast masses. We discuss the demographics of male breast tumors, describe the diagnostic algorithm for evaluating male breast masses, and review the imaging features of rare breast masses and mimickers of male breast cancer.

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Case Report: Ductal CarcinomaIn Situin the Male Breast

Cited by 6 publications

References 3 publications

Pure Ductal Carcinoma in Situ in The Male Breast: A Rare Entity

Pure Ductal Carcinoma in Situ in The Male Breast: A Rare Entity

Magnetic resonance imaging findings of high-grade ductal carcinoma in situ of the male breast: A case report

Unusual Male Breast Lesions

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