Case Report: Epidural and Bilateral Retroorbital Hematomas Complicating Sickle Cell Anemia

Karacostas, Dimitris; Artemis, N.; Papadopoulou, Maria; Christakis, John

doi:10.1097/00000441-199108000-00008

Cited by 35 publications

(23 citation statements)

References 3 publications

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“…In the other reported cases, the EDH was small enough to be managed conservatively [11,17,19,21,27,40]. There are very few cases in the literature where sickle-cell disease has caused other neurosurgical complications [1,23].…”

Section: Discussionmentioning

confidence: 94%

A review of spontaneous intracranial extradural hematoma in sickle-cell disease

et al. 2015

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Sickle-cell disease is common among patients of Afro-Caribbean origin. Though it can precipitate neurological conditions, it only rarely causes neurosurgical problems, with very few reported cases. We describe the case of a 7-year-old girl with a background of sickle-cell disease (SCD) brought into an acute neurosurgical unit in extremis, signs of a raised ICP, and with no history of recent trauma. Following further investigations, an acute drop in the hemoglobin and hematocrit levels were noted, with the cause of her presentation being attributed to a sickling crisis causing skull convexity infarction and resulting in spontaneous bilateral extradural hematomas requiring emergency evacuation. We review the current literature and propose the pathophysiological mechanism behind this phenomenon.

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Section: Discussionmentioning

confidence: 94%

A review of spontaneous intracranial extradural hematoma in sickle-cell disease

et al. 2015

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“…With acute swelling, pain, and erythema of the periorbital area, orbital cellulitis must be ruled out. It is not uncommon to find orbital infarction manifesting concurrently with vasoocclusive crises of anatomically distant areas [4, 9], although our patient presented with an isolated orbital crisis.…”

Section: Discussionmentioning

confidence: 88%

“…Patients may have proptosis due to hematomas in the orbit, which are thought to develop because of vessel wall necrosis [9]; our case was no exception. With acute swelling, pain, and erythema of the periorbital area, orbital cellulitis must be ruled out.…”

Section: Discussionmentioning

confidence: 96%

Orbital Infarction due to Sickle Cell Disease without Orbital Pain

McBride

Kumar

2016

Case Reports in Ophthalmological Medicine

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Sickle cell disease is a hemoglobinopathy that results in paroxysmal arteriolar occlusion and tissue infarction that can manifest in a plurality of tissues. Rarely, these infarcted crises manifest in the bony orbit. Orbital infarction usually presents with acute onset of periorbital tenderness, swelling, erythema, and pain. Soft tissue swelling can result in proptosis and attenuation of extraocular movements. Expedient diagnosis of sickle cell orbital infarction is crucial because this is a potentially sight-threatening entity. Diagnosis can be delayed since the presentation has physical and radiographic findings mimicking various infectious and traumatic processes. We describe a patient who presented with sickle cell orbital crisis without pain. This case highlights the importance of maintaining a high index of suspicion in patients with known sickle cell disease or of African descent born outside the United States in a region where screening for hemoglobinopathy is not routine, even when the presentation is not classic.

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“…Spontaneous EDH in patients with HbSS often occurred along with skull infarction. [14–8] However, the pathogenesis has not been fully elucidated. At least three pathophysiologic mechanisms have been proposed.…”

Section: Discussionmentioning

confidence: 99%

“…An association with vaso-occlusive crises[1–3] and skull infarction. [4–8] were observed in the few reported cases. With no history of head trauma the pathogenesis of spontaneous EDH in patients with sickle cell anaemia is still not clearly defined.…”

Section: Introductionmentioning

confidence: 99%

Spontaneous Epidural Haematoma in Sickle Cell Anaemia: Case Report and Literature Review

Babatola

Yusuf

Abiola

et al. 2012

J Surg Tech Case Report

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Non traumatic spontaneous epidural Haematoma is a rare and often unmentioned complication of sickle cell disease. It is often associated with skull bone infarction. We report an eighteen year old boy with sickle cell anaemia who developed persistence headache during a vaso-occlusive crisis. Brain computed tomography (CT) revealed a right frontal epidural Haematoma (EDH) compressing on the brain. No other etiologic factor was identified. A right frontal craniotomy and evacuation of the Haematoma was performed and he made good recovery. The possible pathogeneses of this rare condition are discussed.

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Case Report: Epidural and Bilateral Retroorbital Hematomas Complicating Sickle Cell Anemia

Cited by 35 publications

References 3 publications

A review of spontaneous intracranial extradural hematoma in sickle-cell disease

A review of spontaneous intracranial extradural hematoma in sickle-cell disease

Orbital Infarction due to Sickle Cell Disease without Orbital Pain

Spontaneous Epidural Haematoma in Sickle Cell Anaemia: Case Report and Literature Review

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