Case Report: Generalized Mutual Information (GMI) Analysis of Sensory Motor Rhythm in a Subject Affected by Facioscapulohumeral Muscular Dystrophy after Ken Ware Treatment

Abstract

In this case report we study the dynamics of the SMR band in a subject affected from Facioscapulohumeral Muscular Dystrophy and subjected to Ken Ware Neuro Physics treatment. We use the Generalized Mutual Information (GMI) to analyze in detail the SMR band at rest during the treatment. Brain dynamics responds to a chaotic-deterministic regime with a complex behaviour that constantly self-rearranges and self-organizes such dynamics in function of the outside requirements. We demonstrate that the SMR chaotic dynamics responds directly to such regime and that also decreasing in EEG during muscular activity really increases its ability of self-arrangement and self-organization in brain. The proposed novel method of the GMI is arranged by us so that it may be used in several cases of clinical interest. In the case of muscular dystrophy here examined, GMI enables us to quantify with accuracy the improvement that the subject realizes during such treatment.

Chaos, Fractal and Recurrence Quantification Analysis of Surface Electromyography in Muscular Dystrophy

“…To such standard procedures, we add nonlinear-chaotic deterministic methods, using the standard procedure to reconstruct phase space of the given sEMG time series evaluating in particular the Embedding Dimension, the Lyapunov Exponents, the Correlation Dimension (fractal dimension), and LZ complexity [2] [3]. We also use the technique of the Generalized Mutual Information and Partial Mutual Information for estimation of synchronization and coupling among regions of interest [9]. In addition, we use the method of the Recurrence Quantification Analysis, RQA [10].…”

“…The present paper is devoted to the study of muscular dystrophy (facioscapulohumeral muscular dystrophy) where it used the treatment NPT that is due to one of the present authors (KW). Since all the details on the basic methods that were used have been reported by us recently in previous published papers [9] [12], we invite the reader to examine such previous papers and we will not give here further indications.…”

“…We will not report details on the clinical case, on the methods of clinical investigation, on the pathogenesis and on the clinical manifestations as well as considerations on the incidence rate of muscular dystrophy in population. The reason is that we have outlined in the greatest detail all such features in our previous publications in [9] [12] [13]. Therefore, for shortness and in order to give the readers very articulated information on the clinical profile and that we could not realize here in the due details, we consider such papers [9] [12] [13] as integrating section also avoiding in this manner to overload the reader with a lot of information and discussions.…”

“…The reason is that we have outlined in the greatest detail all such features in our previous publications in [9] [12] [13]. Therefore, for shortness and in order to give the readers very articulated information on the clinical profile and that we could not realize here in the due details, we consider such papers [9] [12] [13] as integrating section also avoiding in this manner to overload the reader with a lot of information and discussions. Therefore, with the following section, the reader will find directly the results of the present investigation.…”

Verification of the Validity of the NPT Treatment in Hereditary Spastic Paraplegia: An Investigation Performed by Application of Random Matrix Theory

“…Hereditary spastic paraplegia was first described in 1883 by Adolph Strümpell, a German neurologist, and was later described more extensively in 1888 by Maurice Lorrain, a French physician. HSP represents a group of inherited diseases whose main feature is progressive stiffness and contraction (spasticity) in the lower limbs [49] as a result of damage or dysfunction of the nerves [50] [51].…”