Case report: primary basal cell carcinoma of the prostate – Histopathological and biological features and recent new findings in its molecular pathology

Abstract

example of Langerhans cell sarcoma transdifferentiating from a follicular lymphoma and will discuss the limited literature in this rare entity. The role of BRAF V600E mutation in prognosis and treatment will also be discussed. References 1. West DS, Dogan A, Quint PS, et al. Clonally related follicular lymphomas and Langerhans cell neoplasms; expanding the spectrum of transdifferentiation. Am J Surg Pathol 2013; 37: 978-86. 2. Wu Y, Chen WY, Yang TX, et al. Langerhans cell sarcoma arising from antecedent Langerhans cell histiocytosis; a case report. Medicine 2019; 98: e14531. 3. Zeng K, Wang Z, Ohshima K, et al. BRAF V600E mutation correlates with suppressive tumor immune microenvironment and reduced disease-free survival in Langerhans cell histiocytosis. Oncoimmunology 2016; 5: e1185582.