Case Report: Radiological Features of Sclerosing Epithelioid Fibrosarcoma in the Right Fibula

Ding, Qiaoling; Shao, Xiaotong; Liu, Xiaocao; Fu, Yanbiao; Huang, Fengbo; Wang, Chao

doi:10.3389/fonc.2020.603127

Cited by 6 publications

(2 citation statements)

References 20 publications

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“…This nding is expected considering the high brous content. Ding et al described MRI ndings in a 19-year-old patient with SEF of the right bula as a T1/T2 hypointense mass with faint peripheral contrast enhancement during the arterial phase and progressive enhancement during the venous phase [13].…”

Section: Discussionmentioning

confidence: 99%

Imaging features of pediatric hepatic sclerosing epithelial fibrosarcoma

Shadmani

2024

Preprint

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Background: Sclerosing epithelioid fibrosarcoma (SEF) is a rare variant of fibrosarcoma that has been described in fewer than a handful of pediatric patients in the literature and in almost all prior publications focused on pathology. There is no description of the imaging features of hepatic SEF in the literature. Patient presentation: A 17-year-old female with chronic abdominal pain and pruritis was found to have a large solid mass in the right hepatic lobe on ultrasonography (US). Further imaging by contrast-enhanced MRI and FDG PET was performed. A core biopsy of the hepatic mass revealed SFE. Two months later, she underwent liver transplantation. On clinical and imaging follow-up up to 24 months after transplantation, no evidence of recurrence or metastasis was identified. Conclusion: This paper presents the first multimodality imaging features of primary hepatic SEF in an adolescent patient.

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Section: Discussionmentioning

confidence: 99%

Imaging features of pediatric hepatic sclerosing epithelial fibrosarcoma

Shadmani

2024

Preprint

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“…On computed tomography (CT), bone SEF presents as a lytic expansile lesion, mostly surrounded by sclerotic rims. Magnetic resonance imaging (MRI) usually shows a hypointense lesion both on T1WI and T2WI, with peripheral contrast enhancement [4,6,9]. Treatment for SEF consists of complete surgical removal of the lesion, with many surgeons preferring an en-bloc resection since it has been shown to reduce local recurrences.…”

Section: Introductionmentioning

confidence: 99%

Sclerosing Epithelioid Fibrosarcoma of the Spine: Diagnosis and Treatment of a Rare Entity

Lima,

Coutada,

Afonso

et al. 2023

Cureus

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Sclerosing epithelioid fibrosarcoma (SEF) is a rare subtype of sarcoma with high rates of local recurrence and distant metastasis. Morphologically, it resembles other mesenchymal and non-mesenchymal tumors, making it a diagnostic challenge. Treatment relies mostly on surgery with adjuvant chemotherapy or radiotherapy (RT).A 46-year-old woman who presented with lumbar pain and weight loss underwent a computed tomography (CT) scan, magnetic resonance imaging (MRI), and a [18F]-fluorodeoxyglucose positron emission tomography-computed tomography (18F-FDG PET/CT) scan, which showed a lesion involving the L5 vertebra. An incisional biopsy of the lesion established the diagnosis of SEF, with diffuse expression of MUC4 and focal expression of EMA.The patient was treated with neoadjuvant RT followed by surgery. Histology was congruent with the previous diagnosis and demonstrated post-radiation changes.In conclusion, SEF is an aggressive type of sarcoma that is easily misdiagnosed, so it is important to consider it in the differential diagnosis to avoid unbeneficial treatments and a detriment to patient survival.

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