1988
DOI: 10.1016/s0022-5347(17)42313-5
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Castleman’s Disease: An Unusual Retroperitoneal Mass

Abstract: Castleman's disease (angiofollicular lymph node hyperplasia) rarely presents as an isolated retroperitoneal mass radiographically indistinguishable from retroperitoneal malignancies. We report a case of the hyaline vascular variant of Castleman's disease presenting as a calcified pararenal mass. Computerized tomography and nuclear magnetic resonance imaging of this lesion are presented, and its clinical behavior and management are discussed.

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Cited by 29 publications
(18 citation statements)
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“…In contrast, the plasma cell variant is frequently associated with various signs and symptoms such as hypergammaglobulinemia, elevated ESR, anemia and pyrexia. [2][3][4] Furthermore, both variants can be either unicentric or multicentric. Multicentric forms may display a more aggressive course and have frequently been associated with infectious complications.…”
Section: Discussionmentioning
confidence: 99%
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“…In contrast, the plasma cell variant is frequently associated with various signs and symptoms such as hypergammaglobulinemia, elevated ESR, anemia and pyrexia. [2][3][4] Furthermore, both variants can be either unicentric or multicentric. Multicentric forms may display a more aggressive course and have frequently been associated with infectious complications.…”
Section: Discussionmentioning
confidence: 99%
“…Multicentric forms may display a more aggressive course and have frequently been associated with infectious complications. 2,3 The incidence of malignancies, in particular lymphoma and Kaposi's sarcoma, has already been reported in patients with multicentric Castleman's disease. 4,5 The association between unicentric Castleman's disease and vascular neoplasm has also been described previously.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The first case of CD in the retroperitoneum was described by Pietra [4] in 1964. In a review of 315 cases of CD 21 (7%) retroperitoneal tumors were described with six (2%) having a pararenal location [5].…”
Section: Discussionmentioning
confidence: 99%
“…Benign retroperitoneal tumors are rare conditions, comprising only about 20% of all primary retroperitoneal neoplasm's [1]. Castleman's disease is a heterogeneous group of lymphoproliferative disorders with unknown etiology presenting with lymphadenopathy.…”
Section: Introductionmentioning
confidence: 99%