Catalytic, Asymmetric, Bromine-Induced Semipinacol Rearrangements at Unactivated Double Bonds

Abstract

A new catalyst system for the enantioselective bromineinduced semipinacol rearrangement of cyclic allylic alcohols is described. Using the commercially available (DHQD) 2 Pyr catalyst the products containing an all-carbon quaternary chiral centre can be obtained in good yield and high enantioselectivity.