“…However, for panic disordered subjects, a period of sitting without distraction within an unfamiliar laboratory environment would likely represent a relatively threatening, anxiogenic situation (Grillon, 2008;Fonteyne et al, 2009;Pfaltz et al, 2009). For example, compared to healthy controls, individuals with PD are more likely to rate a confined laboratory environment as anxiety provoking (Argyle, 1991) and, when anxious, are especially prone to become hypervigilant for bodily sensations that may signify impending panic (Barlow, 2002;Beck and Clark, 1997;Khawaja and Oei, 1998). As somatic and environmental cues vie for limited attention and neural processing resources (Pennebaker, 2000), somatic cues during REC may have more successfully engaged patients' attention given the absence of visual competition.…”