Catharnthus Alkaloids XXXI: Isolation of Ajmalicine, Pericalline, Tetrahydroalstonine, Vindolinine, and Ursolic acid from Catharanthus Trichophyllus Roots

Catharanthus Alkaloids. XXXVI. Isolation of Vincaleukoblastine (VLB) and Periformyline From Catharanthus trichophyllus and Pericyclivine From Catharanthus roseus

“…The assignments are based on the splitting pattern in the coupled spectra and also on comparison of the chemical shifts with those of model compounds. The aromatic carbon resonances in akuammicine (2) were in accord with those reported for the retuline-like substance (5) by Wenkert et al, (10,17). The cmr spectrum of pericyclivine (4), however, was assigned by the use of off-resonance decoupled spectral information and correlation of carbon resonance frequencies with those of akuammidine (6) (11).…”

“…44, no. 3 DISCUSSION The cmr spectral data of two alkaloids, akuammicine (2) and pericyclivine (4), have been described in table 2. The assignments are based on the splitting pattern in the coupled spectra and also on comparison of the chemical shifts with those of model compounds.…”

Diversity and biological activities of endophytic fungi associated with Catharanthus roseus

“…The plant is a producer of several secondary metabolites and so far around 130 alkaloids alone have been identified [11]. The plant is known for its varied medicinal potential ranging from anticancer, antidiabetic, antihypertensive, antibacterial, antifungal and antioxidant effects [12–14]. This plant has been traditionally used in the treatment of fever, rheumatism and fatigueness.…”