2024
DOI: 10.1111/cns.14812
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Causal relationship and shared genes between air pollutants and amyotrophic lateral sclerosis: A large‐scale genetic analysis

Zhihao Li,
Jie Wen,
Wantao Wu
et al.

Abstract: ObjectiveAir pollutants have been reported to have a potential relationship with amyotrophic lateral sclerosis (ALS). The causality and underlying mechanism remained unknown despite several existing observational studies. We aimed to investigate the potential causality between air pollutants (PM2.5, NOX, and NO2) and the risk of ALS and elucidate the underlying mechanisms associated with this relationship.MethodsThe data utilized in our study were obtained from publicly available genome‐wide association study … Show more

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