This research paper examines the efficacy of the Directorate on Corruption and Economic Offences (DCEO) in combating corruption within Lesotho, while also attempting to establish a correlation with the prevailing poverty conditions in the nation. The investigation was structured around three distinct objectives that facilitated the formulation of pertinent research inquiries. The methodology employed comprised desk reviews designed to identify, validate, and analyze both qualitative and quantitative data sourced from secondary literature to evaluate the operational performance of the DCEO in relation to case load management and successful prosecutions. Data collection was conducted through secondary sources, with subsequent analysis being performed utilizing content analysis techniques, and the results were articulated through thematic organization and narrative presentation. The findings reveal that legal and institutional elements, including the DCEO's autonomy and legal mandate, significantly enhance its capacity to combat corruption in Lesotho. Moreover, various obstacles confronting the organization encompass political interference, limited financial resources, and challenges related to human resources. In light of these findings, it is posited that a systematic reform of the DCEO's operational framework is imperative for advancing its efforts against corruption in Lesotho. This paper further proffers recommendations for the government to make substantial investments in supporting the DCEO to enhance its operational efficiency and effectiveness, along with the removal of any encroachments that impede its performance.