Cause and effect relationship of malnutrition with idiopathic chronic pancreatitis: Prospective case–control study

Abstract

Malnutrition was not a cause of idiopathic chronic pancreatitis and weight loss occurred as an effect of chronic pancreatitis. Cassava was not found to be a cause of idiopathic chronic pancreatitis.

Anthropometric measurements of nutritional status in chronic pancreatitis in India: comparison of tropical and alcoholic pancreatitis

“…These findings suggest that energy undernutrition may not be the cause of TP, but its effect. Our results support and extend those of a previous study on patients with idiopathic CP from subtropical India [15]. Nutritional factors have always been considered to be important in the etiology of CP [25][26][27].…”

“…The small numbers making up the subgroups analyzed is one obvious reason. DM and increased proportion of calories from proteins in diet have been associated with weight loss in patients with idiopathic CP [15]. Resting energy expenditure is raised in CP [31].…”

“…Patients with hereditary pancreatitis, corrected serum calcium value >11 mg/dL, and those with pancreatic cancer as evidenced by CT scan and/or elevated CA 19-9 levels were excluded from the study, as were those with pseudocysts, ascites, and duodenal or biliary obstruction. The patients were said to have ACP if they drank more than 40 g of alcohol per day for at least five years [15]. TP was diagnosed by excluding other causes of chronic pancreatitis.…”

Is the profile of chronic pancreatitis in India changing?

“…It has to be recognized that with economic development and social changes occurring in India, the prevalence of malnutrition is decreasing and per capita alcohol consumption is increasing. Clinical observations from Kerala where the TCP was first described also show a changing profile of CP with the patients being much older, less malnourished, less often diabetic, and having less advanced disease in the 2000s than in the 1980s [4,19].…”

Environmental Risk Factors for Chronic Pancreatitis and Pancreatic Cancer

“…In a prospective case-control trial by Midha et al [11], malnutrition was investigated in the context of chronic pancreatitis in India. The authors focused on patients with idiopathic pancreatitis (i.e.…”