Cd-induced signaling pathways in plants: Possible regulation of PC synthase by protein phosphatase 1

Lima, Ana; Silva, Edgar da Cruz e; Figueira, Etelvina

doi:10.1016/j.envexpbot.2011.12.036

Cited by 4 publications

(4 citation statements)

References 34 publications

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“…Furthermore, in a recent research by Lima et al. (), phytochelatin synthase activity was shown to be possibly modulated by protein phosphorylation, which may lead to new ways to target phytochelatin synthase activity and enhance Cd uptake and tolerance.…”

Section: The Role Of Plants In Cleaning Up Cd‐contaminated Soilsmentioning

confidence: 99%

“…In addition, the overexpression of phytochelatin synthase, a key enzyme catalyzing the final step of PC biosynthesis in rice, can be used as a potential mechanism to enhance the tolerance of plants to Cd stress (Venkataramaiah et al 2011). Furthermore, in a recent research by Lima et al (2012), phytochelatin synthase activity was shown to be possibly modulated by protein phosphorylation, which may lead to new ways to target phytochelatin synthase activity and enhance Cd uptake and tolerance.…”

Section: The Role Of Plants In Cleaning Up Cd-contaminated Soilsmentioning

confidence: 99%

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What is new in the research on cadmium‐induced stress in plants?

Azevedo

Gratão

Monteiro

et al. 2012

Food and Energy Security

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Cadmium (Cd) is an important metal due to its industrial use but also one of the most dangerous metals because of its accumulation in the environment. This can eventually lead to entrance into the food chain if the Cd is taken up by crop plants used for feeding animals and humans. Thus, a large number of reviews have discussed the many aspects of stress induced by Cd and other metals in a wide range of species. In relation to plants, useful reviews have been published over the years regarding molecular and biochemical aspects of Cd stress. In this minireview, we have concentrated on promising and emerging topics of Cd‐stress research in plants, such as hormonal control of the antioxidant system and interaction between organisms and plants.

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Section: The Role Of Plants In Cleaning Up Cd‐contaminated Soilsmentioning

confidence: 99%

Section: The Role Of Plants In Cleaning Up Cd-contaminated Soilsmentioning

confidence: 99%

What is new in the research on cadmium‐induced stress in plants?

Azevedo

Gratão

Monteiro

et al. 2012

Food and Energy Security

View full text Add to dashboard Cite

show abstract

“…) as well as in vivo (Lima et al. ); we did not examine the influence of phosphorylation on PC synthase activity.…”

Section: Discussionmentioning

confidence: 99%

“…This greater sensitivity of TpPCS1 to Cd may be due to the decreased number of cysteines in its C-terminal. In AtPCS1, Cd has also been shown to have an influence on phosphorylation which in turn has been shown to influence activity in vitro (Wang et al 2009) as well as in vivo (Lima et al 2012); we did not examine the influence of phosphorylation on PC synthase activity.…”

Section: Methodsmentioning

confidence: 99%

Characterization of a High Affinity Phytochelatin Synthase from The Cd‐Utilizing Marine Diatom Thalassiosira pseudonana

Gupton-Campolongo

Damasceno

Ahner

2012

Journal of Phycology

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Phytochelatin synthase (PC synthase) is the enzyme that catalyzes the production of phytochelatins, peptides of the structure (γ-Glu-Cys)n -Gly, where n = 2-11, from the sulfhydryl-containing tripeptide glutathione, in response to elevated metal exposure. Biochemical utilization of Cd in the marine diatom Thalassiosira weissfloggi, as well as unusually high ratios of PC to Cd in some Thalassiosira species including T. pseudonana Hasle et Heimdal, motivated the characterization of T. pseudonana PC synthase 1 (TpPCS1). This enzyme is the product of one of three genes in the T. pseudonana genome predicted to encode for a PC synthase based on its homology to canonical PC synthases previously examined. TpPCS1 was cloned, expressed in Escherichia coli and purified under both aerobic and anaerobic conditions. TpPCS1 exhibits several characteristics that set it distinctly apart from the well-studied PC synthase, Arabidopsis thaliana PCS1 (AtPCS1). It is extremely sensitive to oxidation, which suppresses activity, and it is readily inhibited by the addition of Cd in the absence of thiolate ligands. TpPCS1 also has significantly greater affinity for one of its key substrates, the bis-glutathionato-Cd complex. TpPCS1 kinetics is best described by a ternary complex model, as opposed to the ping-pong model used to describe AtPCS1 kinetics. The findings indicate that although the function of TpPCS1 is synonymous to that of AtPCS1, its divergent biochemistry suggests adaptation of this enzyme to the distinct trace metal chemistry of the marine environment and the unique physiological needs of T. pseudonana.

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Cadmium Bioavailability, Uptake, Toxicity and Detoxification in Soil-Plant System

Shahid

Dumat

Khalid

et al. 2016

Reviews of Environmental Contamination and Toxicology

231

175

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This review summarizes the findings of the most recent studies, published from 2000 to 2016, which focus on the biogeochemical behavior of Cd in soil-plant systems and its impact on the ecosystem. For animals and people not subjected to a Cd-contaminated environment, consumption of Cd contaminated food (vegetables, cereals, pulses and legumes) is the main source of Cd exposure. As Cd does not have any known biological function, and can further cause serious deleterious effects both in plants and mammalian consumers, cycling of Cd within the soil-plant system is of high global relevance.The main source of Cd in soil is that which originates as emissions from various industrial processes. Within soil, Cd occurs in various chemical forms which differ greatly with respect to their lability and phytoavailability. Cadmium has a high phytoaccumulation index because of its low adsorption coefficient and high soil-plant mobility and thereby may enter the food chain. Plant uptake of Cd is believed to occur mainly via roots by specific and non-specific transporters of essential nutrients, as no Cd-specific transporter has yet been identified. Within plants, Cd causes phytotoxicity by decreasing nutrient uptake, inhibiting photosynthesis, plant growth and respiration, inducing lipid peroxidation and altering the antioxidant system and functioning of membranes. Plants tackle Cd toxicity via different defense strategies such as decreased Cd uptake or sequestration into vacuoles. In addition, various antioxidants combat Cd-induced overproduction of ROS. Other mechanisms involve the induction of phytochelatins, glutathione and salicylic acid.

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Cd-induced signaling pathways in plants: Possible regulation of PC synthase by protein phosphatase 1

Cited by 4 publications

References 34 publications

What is new in the research on cadmium‐induced stress in plants?

What is new in the research on cadmium‐induced stress in plants?

Characterization of a High Affinity Phytochelatin Synthase from The Cd‐Utilizing Marine Diatom Thalassiosira pseudonana

Cadmium Bioavailability, Uptake, Toxicity and Detoxification in Soil-Plant System

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