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Parmer, J. Norman; Allen, Leeanna; Walton, Wanda

doi:10.1097/01.naj.0000521946.45448.90

Cited by 7 publications

(3 citation statements)

References 16 publications

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“…A few patients had an underlying condition that was known to increase the risk of TB such as HIV infection, rheumatic diseases, or oral immunosuppressants [11]. In addition, diabetes is a risk factor for tuberculosis [11]. In this group one patient had HIV infection and 5 cases had diabetes history.…”

Section: Discussionmentioning

confidence: 96%

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CT Imaging Manifestations of Tubercular Aortic Aneurysm

Xing

Sun

Chen

et al. 2021

Preprint

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Tubercular aortic aneurysm is a rare complication of tuberculosis but associated with very high mortality. Early diagnosis is critical, however, it is challenging due to nonspecific symptoms. This study summarized the CT features of tubercular aortic aneurysm in order to assist timely clinical diagnosis. Seventeen patients with confirmed tubercular aortic aneurysm between 2016 and 2020 were included in this study. The clinical manifestations, past medical history, laboratory and imaging examinations, treatments and other data were collected. CT angiography was routinely performed in all patients. Clinical and CT imaging data was collected and analyzed. All tuberculous aneurysms were pseudoaneurysms, which were located in the thoracic aorta, abdominal aorta, junction of thoracic and abdominal aorta or iliac aorta. The shapes of aneurysms were saccular or lobular. The diameter of aneurysm ranged from 30 to 120 mm. Thirteen patients had atherosclerosis. Mural thrombus was shown in 14 patients. Twelve patients showed enlarged lymph nodes which were found closely related to the aneurysm. Nine patients had tuberculous spondylitis including tuberculosis of thoracic lumbar and lumbosacral spine. Psoas abscess was showed in four patients and iliopsoas abscess was in one patient. Compared with other infectious aneurysms, tuberculous aneurysms typically show more cystic and lobulated shapes on CT scan, which are imaged as poured and unstressed. Another point of differential diagnosis is that the surrounding tissues and adjacent organs of tubercular aneurysms are usually infected with tuberculosis and most of them are accompanied by other sites of tuberculosis.

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Section: Discussionmentioning

confidence: 96%

“…The concentration of CRP and ESR were high in all patients of this group, although cultures of the blood were negative. A few patients had an underlying condition that was known to increase the risk of TB such as HIV infection, rheumatic diseases, or oral immunosuppressants [11]. In addition, diabetes is a risk factor for tuberculosis [11].…”

Section: Discussionmentioning

confidence: 99%

CT Imaging Manifestations of Tubercular Aortic Aneurysm

Xing

Sun

Chen

et al. 2021

Preprint

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“…TB of any type was diagnosed on presentation in all of our cases. A few patients had an underlying condition that is known to increase the risk of TB such as HIV infection, diabetes, or oral immunosuppressants [ 9 ]. Most of the reported cases of TBAA are symptomatic, but the symptoms are nonspecific and depend on the size, position, and rapid growth of the aneurysm.…”

Section: Discussionmentioning

confidence: 99%

CT Imaging Manifestations of Tuberculous Aortic Aneurysm

Xing¹,

Sun²,

Chen³

et al. 2022

Rev. Cardiovasc. Med.

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Background: Tuberculous aortic aneurysm (TBAA) is a rare complication of TB and is associated with high mortality. Early diagnosis is critical; however, it is challenging due to nonspecific symptoms. This study summarized the computed tomography (CT) features of TBAA with the aim of assisting with timely clinical diagnosis. Methods: Seventeen patients with TBAA between 2015 and 2020 were included in this study. The clinical manifestations, past medical history, laboratory and imaging examinations, treatments, and other data were collected and analyzed. CT angiography was performed in all patients. Results: All tuberculous aneurysms were pseudoaneurysms, which were located in the thoracic aorta (8/17, 47%), abdominal aorta (7/17, 41%), junction of the thoracic and abdominal aorta (1/17, 6%) or abdominal aorta and iliac artery (1/17, 6%) region. The shapes of all aneurysms were saccular, and nine of them were lobulated. The aneurysm diameter ranged from 3 to 12 cm. Of the 17 patients, 12 (71%) had calcification; 14 (82%) had intraluminal thrombus; 12 (71%) showed enlarged lymph nodes, which were closely related to the aneurysm; and 9 (53%) had tuberculous spondylitis including TB of the thoracic lumbar and lumbosacral spine. Psoas abscess was detected in 4 (23%) patients and iliopsoas abscess was detected in 1 (6%) patient. Conclusions: TBAA typically shows mycotic shapes on CT scans. Another feature is that the surrounding tissues and adjacent organs of tubercular aneurysms are usually infected with TB, and most of them are accompanied by other sites of TB.

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