Cefoxitin and Ciprofloxacin Neurotoxicity and Catatonia in a Patient on Hemodialysis

Denysenko, Lex; Nicolson, Stephen E.

doi:10.1016/j.psym.2011.01.016

Cited by 14 publications

(7 citation statements)

References 21 publications

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“…Other frequent reasons for FQ administration were bacteriemia [ 24 , 43 , 61 , 74 , 78 ] and perioperative prophylaxis [ 25 , 35 , 43 , 56 , 71 , 81 ]. In a small number of cases, FQs were used for the treatment of prostatitis [ 50 ], pelvic inflammatory disease [ 72 ], tuberculosis [ 57 ], osteoarticular infections [ 49 ], sinusitis [ 17 , 38 ], conjunctivitis [ 58 ], meningitidis [ 64 ], abscesses [ 16 , 51 ], and ulcers [ 37 ]. In two cases, FQs were introduced as an empirical treatment [ 27 , 66 ].…”

Section: Resultsmentioning

confidence: 99%

“…Other medications simultaneously administered were paracetamol (6/71) [ 17 , 19 , 27 , 29 , 73 , 75 ] and non-steroidal anti-inflammatory drugs (NSAIDs) (4/71) [ 14 , 40 , 62 , 73 ]. In 11 cases, patients were treated with psychoactive drugs, including opioids [ 20 , 25 , 27 , 51 , 64 , 81 ], antipsychotics [ 31 , 81 ], benzodiazepines [ 25 , 27 , 64 ], 5-hydroxytryptamine antagonists [ 25 , 68 , 69 ], antiepileptic drugs [ 31 , 69 ], dopamine agonists [ 66 ], and antidepressants [ 31 , 72 ]. Theophylline was used in one case [ 32 ].…”

Section: Resultsmentioning

confidence: 99%

“…Some cases of autoimmune diseases were noted, including multiple sclerosis [ 24 , 31 ], Sjogren’s syndrome [ 20 , 24 ], rheumatoid arthritis [ 20 ], ulcerative colitis [ 56 ], primary sclerosing cholangitis [ 56 ], and lupus erythematosus [ 74 ]. A past medical history of psychiatric disorders, including schizoaffective disorder [ 31 ], depression [ 50 , 51 , 55 , 72 ], suicidal behavior [ 50 ], and psychosis [ 20 ], was found. Parkinson’s disease was noted in one case [ 66 ].…”

Section: Resultsmentioning

confidence: 99%

“…A few cases of substance abuse, including alcohol [ 40 ], tobacco [ 14 ] and marijuana [ 44 , 78 ] smoking, and cocaine abuse [ 51 ], were noted.…”

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Depressive and Other Adverse CNS Effects of Fluoroquinolones

Wierzbiński¹,

Hubska

Henzler

et al. 2023

Pharmaceuticals

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Fluoroquinolones (FQs) are widely used drugs around the world. This is a result of their broad spectrum of antibacterial activity, high bioavailability, and known efficacy. Since they appeared on the market, their prescribing frequency has gradually increased. In 2011, FQs became the third most prescribed class of antibiotics in the US. Widespread use of these drugs resulted in an increasing number of reported side effects. In 2016, the FDA warned about significant side effects, including mental disorders in the form of anxiety, psychotic symptoms, insomnia, and depression. Psychiatric adverse reactions to FQs occur with a frequency of 1 to 4.4% and the mechanism of their formation is not entirely clear. It is believed that the antagonistic effect of FQs on the GABA receptor or interaction with the main receptor for the glutamatergic system—NMDA—is responsible for this. The paper is a structured review of 68 selected publications and the latest summary of CNS adverse effects that occur during FQ use. Prescribers should be aware of the risk factors for FQ toxicity, including elderly patients with underlying medical conditions or receiving concomitant medication; however, these adverse events may also occur in other groups of patients.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…A few cases of substance abuse, including alcohol [ 40 ], tobacco [ 14 ] and marijuana [ 44 , 78 ] smoking, and cocaine abuse [ 51 ], were noted.…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

Depressive and Other Adverse CNS Effects of Fluoroquinolones

Wierzbiński¹,

Hubska

Henzler

et al. 2023

Pharmaceuticals

View full text Add to dashboard Cite

show abstract

“…Catatonia, including malignant catatonia ( Nomura et al, 2021 ), has been described in the context of severe renal impairment ( Carroll et al, 1994 ; Desai et al, 1984 ; Fekete, 2013 ), in patients receiving dialysis ( Denysenko and Nicolson, 2011 ) and in the post-transplantation period, often as a result of drug toxicities ( Quinn et al, 2014 ; Sikavi et al, 2019 ). Patients with renal impairment, even those on dialysis, may still be able to tolerate and benefit from benzodiazepines ( Tsai and Huang, 2010 ) with consideration of the severity of renal impairment, route of administration of benzodiazepines, comorbidities (e.g.…”

Section: Considerations In Special Groups and Situationsmentioning

confidence: 99%

Evidence-based consensus guidelines for the management of catatonia: Recommendations from the British Association for Psychopharmacology

et al. 2023

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The British Association for Psychopharmacology developed an evidence-based consensus guideline on the management of catatonia. A group of international experts from a wide range of disciplines was assembled. Evidence was gathered from existing systematic reviews and the primary literature. Recommendations were made on the basis of this evidence and were graded in terms of their strength. The guideline initially covers the diagnosis, aetiology, clinical features and descriptive epidemiology of catatonia. Clinical assessments, including history, physical examination and investigations are then considered. Treatment with benzodiazepines, electroconvulsive therapy and other pharmacological and neuromodulatory therapies is covered. Special regard is given to periodic catatonia, malignant catatonia, neuroleptic malignant syndrome and antipsychotic-induced catatonia. There is attention to the needs of particular groups, namely children and adolescents, older adults, women in the perinatal period, people with autism spectrum disorder and those with certain medical conditions. Clinical trials were uncommon, and the recommendations in this guideline are mainly informed by small observational studies, case series and case reports, which highlights the need for randomised controlled trials and prospective cohort studies in this area.

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Neurological and Psychiatric Side Effects of Antimicrobials

Bangert

Hasbun

2020

Current Clinical Neurology

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Cefoxitin and Ciprofloxacin Neurotoxicity and Catatonia in a Patient on Hemodialysis

Cited by 14 publications

References 21 publications

Depressive and Other Adverse CNS Effects of Fluoroquinolones

Depressive and Other Adverse CNS Effects of Fluoroquinolones

Evidence-based consensus guidelines for the management of catatonia: Recommendations from the British Association for Psychopharmacology

Neurological and Psychiatric Side Effects of Antimicrobials

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