Celiac disease and endometriosis: what is the nexus?

Mormile, Raffaella; Vittori, Giorgio

doi:10.1007/s00404-013-2928-3

Cited by 2 publications

(1 citation statement)

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“…Concomitant CD and endometriosis may render the diagnosis difficult due to the overlapping symptoms, such as abdominal pain, bowel changes, spontaneous abortion, and infertility (33) . In the present study, endometriosis was diagnosed in 3.1% of the patients (5/161) at the diagnosis of CD.…”

Section: Discussionmentioning

confidence: 99%

Immune Mediated Diseases in Patients With Celiac Disease and Their Relatives: A Comparative Study of Age and Sex

Kotze

Moreno

et al. 2018

Arq. Gastroenterol.

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BACKGROUND: Up to 15% of other immune-mediated diseases (IMDs) can occur in patients with CD throughout their lives and are associated with multiple factors, including sex and sex hormone levels. Moreover, sex is associated with differences in clinical presentation, onset, progression, and outcomes of disorders. OBJECTIVE: To investigate the prevalence of IMDs at diagnosis in patients with celiac disease (CD) and their first-degree relatives and to compare the findings between female and male patients of different age. METHODS: A retrospective study including Brazilian patients with CD who visited the same doctor during January 2012 to January 2017 was performed. Demographic and medical history data were collected through self-administered questionnaires and medical charts of the patients. In total, 213 patients were examined at diagnosis: 52 males (mean age, 40.0 years) and 161 females (mean age, 41.4 years). The patients were divided into two groups according to sex and age. RESULTS: IMDs were observed in 60.2% of the female (97/161) and 42.3% of the male patients (22/52; P=0.22). However, the frequency of IMDs was significantly higher in females aged 51-60 years than in males with same age (P=0.0002). Dermatitis herpetiformis (DH) was significantly more prevalent in males (P=0.02), whereas atopy was more prevalent in females (P=0.02). IMDs observed in first-degree relatives were similar to those observed in patients (70.9%; P<0.001), with a higher number observed in female relatives. CONCLUSION: The frequency of IMDs in CD patients was similar in all age groups and both sexes, except women diagnosed with CD after 51 years of age presented with an increased frequency of IMDs compared with males. Dermatitis herpetiformis was more prevalent in males, whereas atopy was more prevalent in females. No difference was observed in the type of IMDs between the first-degree relatives of both sexes.

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Section: Discussionmentioning

confidence: 99%