Celiac disease and selected long-term health issues

Freeman, Hugh James

doi:10.1016/j.maturitas.2012.08.005

Cited by 10 publications

(8 citation statements)

References 64 publications

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“…Nowadays, celiac disease has become a common genetic disease (Hegazy et al, 2009), that affects the small intestine mucosa (Freeman, 2012), with an occurence of 1 in 133-300 persons world wide (Fasano et al, 2003;Fasano and Catasi, 2001;Feighery, 1999). Due to this high occurence, interest for gluten-free products has increased in the market trend, as the number of celiac diseases cases are continuously growing (Ilkem et al, 2010;Maria and Rosell, 2015).…”

Section: Introductionmentioning

confidence: 99%

Effect of sodium carboxymethyl cellulose on gluten-free dough rheology

Nicolae

Radu

Belc³

2016

Journal of Food Engineering

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Section: Introductionmentioning

confidence: 99%

Effect of sodium carboxymethyl cellulose on gluten-free dough rheology

Nicolae

Radu

Belc³

2016

Journal of Food Engineering

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“…Comparably, the review of other reports indicated the possibility of genetics playing a critical role in the development of both obesity and CD. In a study by van Heel et al, it was indicated that CD has a strong genetic component, which is higher compared to other common complex diseases among children and adults [55]. In this study, it was identified that there must be an HLA-DQ2 variant, which is required to cause the dietary antigens to the T cells, in order for CD to occur [55,58].…”

Section: Heredity Of CD and Obesitymentioning

confidence: 79%

“…There have been numerous reports that have indicated a relationship between CD and obesity in the context of heredity. Notably, the diagnosis of CD and obesity among children has, for many years, adopted a familiar approach based on the 'classic' signs and symptoms [54,55]. Although the study from McCrea may be out of date in several ways, he derecognize that the genetic a etiology of CD indicated an increased incidence among people whose relatives have been diagnosed with the disease [56].…”

Section: Heredity Of CD and Obesitymentioning

confidence: 99%

“…The two conditions are more phenotypically and genetically heterogeneous; hence, they are more complex than previously considered. Genetics play an important function in the energetic imbalance that may lead to fat accumulation in cases of obesity, and in CD, the gluten intolerance may as well be associated with genetic factors as proven by some authors [55,65]. Thus, the demonstration of the genetic background associated with obesity and CD is particularly important in determining the correlation between the two health conditions.…”

Section: Heredity Of CD and Obesitymentioning

confidence: 99%

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Failure to Thrive: A Review for a Relationship between Coeliac Disease and Obesity

2018

Medical &Amp; Clinical Research

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Objectives: The primary objective of this review was to provide a systematic review of the literature on the relationship between CD and obesity. Further, the reviewer had the purpose of conducting an investigation on this correlation, ranging from pediatrics to adults, in specific areas such as the mechanism of the two conditions and the nutritional interventions. The mechanism review involved finding any pathogenic and pathophysiological link between the two conditions and investigating the possible association in clinical evidence and manifestations and of the symptoms. As a result, the present research was designed to establish a paper that can effectively inform not only the public but health care providers, concerning the importance of proper and time-sensitive diagnosis. Methods: In order to achieve these objectives, the researcher conducted desk-based research, which involved a comprehensive review of numerous journal articles drawn from various publishers. The search strategy involved the use of both internal and external secondary sources of information obtained from Science Direct, PubMed, Journal of Paediatric Gastroenterology and Nutrition, The American Journal of Clinical Nutrition, and The European Journal of Clinical Nutrition, among others. Moreover, the search strategy also considered the mechanistic pathology, functional physiology, and human intervention. Results: The key pathophysiological findings indicated that CD and obesity have a connection in the context of the predisposing factors, which are genetic, environmental and immunological factors. Further, the two conditions also show connection in the aspects of human nutritional interventions, where the intervention for CD was established to involve a GFD, however, some patients have been recorded as becoming obese once they start the treatment process. Conclusion: Conclusively, it was important establishing a link between obesity and CD based on the clinical implications of the findings, as well as the general healthcare field; where, the present paper points out for the proper diagnosis of both conditions, whether the symptoms are atypical or not. Hence, it was important to provide a precise nutritional intervention for future patients, which may involve an introduction of a GFD before diagnosis, and strict follow-up and education for the patients on the importance of this intervention.

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“…The only effective treatment for CD is a lifelong gluten-free diet (GFD). The strict adherence to a GFD is crucial to resolve symptoms and nutritional deficiencies, but also to avoid clinical complications associated with long-term gluten intake in celiac patients, such as osteoporosis, anemia or malignancy (Freeman 2012). It is generally recommended that individuals suffering CD have a careful therapy follow-up and dietary control.…”

Section: Introductionmentioning

confidence: 99%