Celiac disease in the Red Sea state of Sudan

Ageep, Ali K.

doi:10.7869/tg.2012.28

Cited by 10 publications

(7 citation statements)

References 25 publications

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Section: Epidemiologymentioning

confidence: 99%

“…A Sudanese study where 172 patients with suspected CD were investigated, 128/172 (74%) had confirmed CD and 105/128 (82%) were aged ≤20 years [10]. 64/105 had gastrointestinal symptoms and the remainder (n = 41) had extraintestinal manifestations, such as stunted growth, bone or joint pain, anaemia, skin manifestations and peripheral neuropathy [10]. Another Sudanese study where 38/60 (63%) were aged ≤20 years, revealed the most common symptoms as chronic diarrhoea, followed by iron deficiency anaemia, weight loss, abdominal pain, and delayed growth and puberty [11].…”

Section: Epidemiologymentioning

confidence: 99%

Section: Clinical Featuresmentioning

confidence: 99%

“…Clinical signs and symptoms of CD can be varied, non-specific and wide-ranging as evident from the discussion above [3,[10][11][12][13]. The symptoms can be broadly divided into intestinal and extraintestinal manifestations (Table 1) [1,[10][11][12][13]17]. A study from India showed that the mean age of diagnosis of CD in children presenting with extra-intestinal manifestations was higher (6.9 ± 2.9 years), compared to diarrhoeal-related CD (5.8 ± 2.8 years) [14].…”

Section: Clinical Featuresmentioning

confidence: 99%

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Coeliac disease in children: the need to improve awareness in resource-limited settings

et al. 2019

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Coeliac disease (CD) is an immune-mediated systemic disorder caused by the ingestion of gluten. In children, it may present with intestinal or extra-intestinal manifestations such as diarrhoea, weight loss, iron deficiency anaemia or faltering growth. Diagnosis is confirmed by small bowel biopsies showing histological changes consistent with enteropathy. In 2012, the European Society for Paediatric Gastroenterology, Hepatology and Nutrition revised the CD guidelines and suggested that, in a selective group of symptomatic children, CD can be diagnosed without the need for smallbowel biopsies. Management of CD is through strict adherence to a life-long gluten-free diet (GFD). CD is of great public health significance as its prevalence in developing countries has been found to be similar to that in developed countries. Early recognition and treatment improves prognosis. Patients and families require long term support to enable effective adherence to a GFD lifestyle. This alone can be challenging, but through support of health professionals and dietitians, can improve patient outcomes. In resource-limited settings medical professionals need to be creative in formulating cheaper and locally sourced gluten free options in close cooperation with the dietitians thereby ensuring availability of gluten free food items at affordable prices. In this paper, we gave an overview of the subject followed by authors' view to emphasize the need for improved awareness in resource-limited settings.

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Section: Epidemiologymentioning

confidence: 99%

Section: Epidemiologymentioning

confidence: 99%

Section: Clinical Featuresmentioning

confidence: 99%

Section: Clinical Featuresmentioning

confidence: 99%

See 2 more Smart Citations

Coeliac disease in children: the need to improve awareness in resource-limited settings

et al. 2019

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“…1 They did not discuss the recent publications about coeliac disease in sub-Saharan East Africa, especially in Sudan and Djibouti. 2,3,4 Coeliac disease does exist in inter-tropical Africa, even if HLA DQ2 and DQ8 haplotypes do seem less frequent and coeliac disease seroprevalence is lower in general population. 1,5 We recently published 17 cases of patients with coeliac disease seen in Djibouti between 2005 and 2007.…”

mentioning

confidence: 99%