Cell adhesion evaluation of laser-sintered HAp and 45S5 bioactive glass coatings on micro-textured zirconia surfaces using MC3T3-E1 osteoblast-like cells

Laser surface texturing of zirconia-based ceramics for dental applications: A review

“…By designing regularly patterned surfaces, directional cell alignment, migration, and proliferation can be achieved [186,189]. Cell responses to laser textured zirconia-based ceramics with different patterns, such as grooves [60,190,191], pits [139], and grids [60,192,193], have been reported. Fig.…”

Hydroxyapatite Consolidated by Zirconia: Applications for Dental Implant

“…This method is a hopeful method to progress the direct sintering of HAp on ZrO 2 substrates in order to produce appropriate coatings. It is known that mechanical interlocking produced through laser texturing is able to enhance the stability of the coating interfaces, therefore preventing delamination of coating during the implants insertion [65].…”

“…Mesquita-Guimarães et al [65] sintered HAp coatings and 45S5 bioactive glass on micro-textured ZrO 2 via laser and evaluated osteoblasts-like cell adhesion. In vitro test indicated that, compared to flat surfaces, the squared textured pattern possessed bioactive coating and 100 µm width grooves provided an increase of 90% of cell viability after incubation for 48 hours.…”

Iron (Fe)-doped mesoporous 45S5 bioactive glasses: Implications for cancer therapy

“…As biocompatible materials, bioactive glasses (BGs) have been extensively applied for managing various bone lesions over the past 50 years. The first developed member of the BG family was a silicate-based glass, the so-called 45S5 (Bioglass®), with the composition of 45% SiO 2 , 24.5% Na 2 O, 24.5% CaO, and 6% P 2 O 5 in weight% [ 7 , 8 ]. There is a long history of successful usage of 45S5 BG in the medical setting; other types and formulations of BGs have been developed over the years for different applications [9] .…”