Cellular and Molecular Impact of Green Synthesized Silver Nanoparticles

Abstract

Toxicity and biocompatibility of silver nanoparticles are of a major concern due to their extensive production regardless of their application in current industries. Information about toxicology or biocompatibility is crucial regarding their proper utilization and application in clinical as well as environmental aspect. This chapter describes in detail about the different techniques and technology of synthesis of silver nanoparticles and explains their different physiochemical properties in context of the current research scenario. Further, it also explains the biocompatibility and toxicity of silver nanoparticles at cellular and molecular aspects. The mechanism of their toxicity has been described keeping in view of the recent research done. In brief, it reveals detail knowledge of the cellular and molecular impact of silver nanoparticles.

Molecular nanoinformatics approach assessing the biocompatibility of biogenic silver nanoparticles with channelized intrinsic steatosis and apoptosis

“…The previously documented reports have also mentioned the SPR peak of AgNPs in a range of 400–500 nm. 55 Further, the hydrodynamic size and stability of G-AgNPs and C-AgNPs were determined in the different media used for further toxicological assays. As shown in Fig.…”

SERS activity of hybrid nano/microstructures Ag-Fe3O4 based on Dimorphotheca ecklonis pollen grains as bio-template

“…These compounds have been reported that can act as bio-reducing and capping agents during the biogenic synthesis of nanoparticles [26][27][28] . The synthesis of silver nanoparticles through a bioreduction method allows clean, non-toxic, and environmentally friendly synthesis, others that promotes the obtaining of nanoparticles with less cytotoxicity 29,30 . Silver nanoparticles(AgNPs) was obtained by bio-reduction of Ag +1 ions with phenolic compounds of the exine, furthermore pollen grains serves as a bio-template since promotes the adhesion of silver nanoparticles (Fig.…”

Zebrafish (Danio rerio) as an ecotoxicological model for Nanomaterial induced toxicity profiling

“…ROS reactive oxygen species regulation, apoptosis, and necrosis. In view of these reports, the in vivo toxicity can be described as an effect of dysregulated expression of ROS production, leading to greater apoptosis and other cell death-related phenomena (Patel et al, 2019;Verma et al, 2019).…”